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Action spectrum of the retinal mechanism mediating nocturnal light-induced suppression of rat pineal gland N-acetyltransferase.

作者信息

Bronstein D M, Jacobs G H, Haak K A, Neitz J, Lytle L D

出版信息

Brain Res. 1987 Mar 17;406(1-2):352-6. doi: 10.1016/0006-8993(87)90806-7.

DOI:10.1016/0006-8993(87)90806-7
PMID:3567633
Abstract

The spectral properties of the retinal mechanism mediating the inhibitory effects of nocturnal light on pineal gland N-acetyltransferase (NAT) activity were determined. Pineal gland NAT activity declined linearly in albino rats exposed to different irradiances of a 460 or 580 nm monochromatic light during the middle of the dark phase of the cycle. The difference in sensitivity to the test lights is that predicted for a photopigment having peak absorbance at 495 nm, suggesting the inhibition of pineal gland N-acetyltransferase activity is mediated by the photopigment found in rat rods.

摘要

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