Capaldi Deborah M, Tiberio Stacey S, Kerr David Cr, Owen Lee D
Oregon Social Learning Center, Eugene, OR, USA.
Subst Abuse. 2022 Jun 3;16:11782218221096154. doi: 10.1177/11782218221096154. eCollection 2022.
Associations between men's prior cannabis use and their physical and psychosocial adjustment were examined using prospective data across adolescence (ages 13-20 years), early adulthood (ages 20-30 years), and midadulthood (ages 30-38 years). The theoretical framework was based in developmental-contextual and lifespan approaches.
Models were tested using men in the Oregon Youth Study who had been studied since ages 9 to 10 years and who, in childhood, lived in neighborhoods with higher than average rates of delinquency. Cannabis use in adolescence was used to predict early adult outcomes (and early adult use to midadult outcomes). In addition, a set of covariates was added to the models, including childhood risk factors assessed at age 9 years (ie, family socioeconomic status; externalizing behaviors; and if available, the childhood proxy for the outcome [eg, age 9 intelligence scale]) and alcohol use in adolescence (or early adulthood). physical health outcomes included accidental injuries, problems resulting from a prior injury, body mass index, self-report health, and also pain and cardiovascular risk (blood pressure and pulse rate) in midadulthood. Psychosocial outcomes included income, housing insecurity, intelligence, depressive symptoms, psychosis symptoms, hostility/aggression, social problems, and attention problems.
Whereas there was almost no prediction from prior cannabis use to the physical health outcomes, there were comprehensive associations of cannabis use from the prior developmental period and psychosocial outcomes in both early adulthood and midadulthood.
Cannabis use in prior developmental periods was associated with a broad range of types of poor psychosocial adjustment in adulthood.
利用青少年期（13 - 20岁）、成年早期（20 - 30岁）和成年中期（30 - 38岁）的前瞻性数据，研究了男性先前使用大麻与其身体和心理社会适应之间的关联。理论框架基于发展情境和毕生发展方法。
对俄勒冈青少年研究中的男性进行模型测试，这些男性从9至10岁起就被研究，童年时生活在犯罪率高于平均水平的社区。用青少年期的大麻使用情况预测成年早期的结果（并用成年早期的使用情况预测成年中期的结果）。此外，在模型中加入了一组协变量，包括9岁时评估的童年风险因素（即家庭社会经济地位、外化行为，以及如果有的话，结果的童年代理指标[如9岁时的智力量表]）和青少年期（或成年早期）的酒精使用情况。身体健康结果包括意外伤害、既往损伤导致的问题、体重指数、自我报告的健康状况，以及成年中期的疼痛和心血管风险（血压和脉搏率）。心理社会结果包括收入、住房不安全、智力、抑郁症状、精神病症状、敌意/攻击行为、社会问题和注意力问题。
虽然先前使用大麻对身体健康结果几乎没有预测作用，但在成年早期和成年中期，先前发育阶段的大麻使用与心理社会结果存在全面的关联。
先前发育阶段使用大麻与成年期广泛的不良心理社会适应类型有关。
