Divison of General Internal Medicine and Health Services Research, Department of Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
Division of General Pediatrics, Department of Pediatrics and Children's Discovery and Innovation Institute, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
Subst Use Misuse. 2023;58(9):1080-1089. doi: 10.1080/10826084.2023.2201852. Epub 2023 May 9.
Some patterns of cannabis use may presage risk for long-term negative effects. We examined associations between a novel adolescent cannabis misuse scale and early-adult life course outcomes.
We performed a secondary data analysis of a cohort of Los Angeles, CA high school students from grade 9 through age 21. Participants reported baseline individual demographic and family characteristics at grade 9, adolescent cannabis misuse (8-items) and alcohol misuse (12-items) at grade 10, and outcomes at age 21. We used multivariable regression to model the associations of cannabis misuse scale score with problem substance use (defined as any of: 30-day illegal drug use, 30-day use of another's prescription to get high, hazardous drinking) and several secondary outcomes (behavioral, mental health, academic, social determinants of health), adjusting for covariates. Parallel analyses were conducted for alcohol misuse.
The 1,148 participants (86% retention) were 47% male, 90% Latinx, 87% US born, and 40% native English speakers. Approximately 11.4% and 15.9% of participants reported at least one item on the cannabis and alcohol misuse scales, respectively. At age 21, approximately 6.7% of participants reported problem substance use, which was associated with both Cannabis and Alcohol Misuse Scales (OR 1.31, 95%CI[1.16, 1.49] and OR 1.33, 95%CI[1.18, 1.49], respectively). Both scales were similarly associated with outcomes in all four categories.
The Adolescent Cannabis Misuse Scale is a promising tool for identifying early patterns of substance use that predict future negative outcomes and enabling early intervention at a critical period in youth development.
一些大麻使用模式可能预示着长期负面后果的风险。我们研究了一种新型青少年大麻滥用量表与成年早期生活轨迹结果之间的关联。
我们对来自加利福尼亚州洛杉矶的一组高中生进行了二次数据分析，研究对象从 9 年级到 21 岁。参与者在 9 年级时报告了个人人口统计学和家庭特征的基线数据，在 10 年级时报告了青少年大麻滥用（8 项）和酒精滥用（12 项）情况，并在 21 岁时报告了结果。我们使用多变量回归模型来模拟大麻滥用量表评分与问题物质使用（定义为：30 天内非法药物使用、使用他人处方来获得快感、危险饮酒）和几个次要结果（行为、心理健康、学业、健康的社会决定因素）之间的关联，同时调整了协变量。对酒精滥用进行了平行分析。
1148 名参与者（86%保留率）中，47%为男性，90%为拉丁裔，87%为美国出生，40%为母语为英语。分别约有 11.4%和 15.9%的参与者报告了大麻和酒精滥用量表上至少有一个项目。在 21 岁时，约有 6.7%的参与者报告了问题物质使用，这与大麻和酒精滥用量表都有关（OR 1.31，95%CI[1.16，1.49]和 OR 1.33，95%CI[1.18，1.49]）。两个量表在四个类别中的所有结果都具有相似的相关性。
青少年大麻滥用量表是一种很有前途的工具，可以识别出预测未来负面结果的早期物质使用模式，并在青年发展的关键时期进行早期干预。
