严重急性呼吸综合征冠状病毒2与可能的肺癌风险。
SARS-CoV-2 and probable lung cancer risk.
作者信息
Khiali Sajad, Rezagholizadeh Afra, Entezari-Maleki Taher
机构信息
Department of Clinical Pharmacy, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran.
Cardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
出版信息
Bioimpacts. 2022;12(3):291-292. doi: 10.34172/bi.2022.23266. Epub 2022 Mar 26.
Abstract
The pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become a global crisis with a growing number of mortalities and morbidities worldwide. Despite performing numerous researches, there are still considerable unrevealed details regarding the long-term complications and post-infection immunity of the coronavirus disease 2019 (COVID-19). Based on pathophysiological features, SARS-CoV-2 may act similarly as an oncovirus in the lung. This letter summarized three possible oncogenic mechanisms of SARS-CoV-2 that may be associated with lung cancer development.
摘要
严重急性呼吸综合征冠状病毒2（SARS-CoV-2）大流行已成为一场全球危机，全球范围内的死亡和发病数量不断增加。尽管进行了大量研究，但关于2019冠状病毒病（COVID-19）的长期并发症和感染后免疫，仍有相当多未揭示的细节。基于病理生理特征，SARS-CoV-2在肺部的作用可能类似于肿瘤病毒。这封信总结了SARS-CoV-2可能与肺癌发生相关的三种致癌机制。
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