Bonanad Clara, Esteve-Claramunt Francisca, García-Blas Sergio, Ayesta Ana, Díez-Villanueva Pablo, Pérez-Rivera Jose-Ángel, Ferreiro José Luis, Cánoves Joaquim, López-Fornás Francisco, Ariza Solé Albert, Raposerias Sergio, Vivas David, Blanco Regina, Bompart Berroterán Daznia, Cordero Alberto, Núñez Julio, Fácila Lorenzo, Núñez-Gil Iván J, Górriz José Luis, Bodí Vicente, Martínez-Selles Manuel, Ruiz Nodar Juan Miguel, Chorro Francisco Javier
Cardiology Department, Clinic University Hospital of Valencia, 46010 Valencia, Spain.
INCLIVA Biomedical Research Institute, 46010 Valencia, Spain.
J Clin Med. 2022 May 26;11(11):3008. doi: 10.3390/jcm11113008.
The treatment of acute coronary syndrome (ACS) in elderly patients continues to be a challenge because of the characteS.G.B.ristics of this population and the lack of data and specific recommendations. This review summarizes the current evidence about critical points of oral antithrombotic therapy in elderly patients. To this end, we discuss the peculiarities and differences reported referring to dual antiplatelet therapy (DAPT) in ACS management in elderly patients and what might be the best option considering these population characteristics. Furthermore, we analyze antithrombotic strategies in patients with atrial fibrillation (AF), with a particular focus on those cases that also present coronary artery disease (CAD). It is imperative to deepen our knowledge regarding the management of these challenging patients through real-world data and specifically designed geriatric studies to help resolve the questions remaining in their disease management.
由于老年人群的特点以及缺乏相关数据和具体建议，老年急性冠状动脉综合征（ACS）的治疗仍然是一项挑战。本综述总结了目前关于老年患者口服抗栓治疗关键点的证据。为此，我们讨论了老年患者ACS管理中双重抗血小板治疗（DAPT）的特殊性和差异，以及考虑到这些人群特征可能的最佳选择。此外，我们分析了心房颤动（AF）患者的抗栓策略，特别关注那些同时患有冠状动脉疾病（CAD）的病例。必须通过真实世界的数据和专门设计的老年研究来加深我们对这些具有挑战性患者管理的认识，以帮助解决其疾病管理中仍存在的问题。
