Prokisch József, El-Ramady Hassan, Daróczi Lajos, Nagy Éva, Badgar Khandsuren, Kiss Attila, Shaikh Ayaz Mukarram, Gilányi Ibolya, Oláh Csaba
Institute of Animal Science, Biotechnology and Nature Conservation, Faculty of Agricultural and Food Sciences and Environmental Management, University of Debrecen, Böszörményi út 138, 4032 Debrecen, Hungary.
Soil and Water Department, Faculty of Agriculture, Kafrelsheikh University, Kafr El-Sheikh 33516, Egypt.
Plants (Basel). 2022 May 24;11(11):1391. doi: 10.3390/plants11111391.
The human blood sugar level is important and should be controlled to avoid any damage to nerves and blood vessels which could lead to heart disease and many other problems. Several market-available treatments for diabetes could be used, such as insulin therapy, synthetic drugs, herbal drugs, and transdermal patches, to help control blood sugar. In a double-blind human study, four kinds of honey from bees fed on acacia, sea buckthorn, chlorella alga, and green walnut extracts were used in fortifying yogurt for controlling human blood sugar. The impact of a previously fortified honey was investigated on blood levels and other parameters of healthy individuals in a human study with 60 participants. The participants received 150 mL of yogurt mixed with 30 g of honey every morning for 21 days. Before and after the study period, the basic blood parameters were tested, and the participants filled out standardized self-report questionnaires. Acacia honey was the traditional honey used as a control; the special honey products were produced by the patented technology. The consumption of green walnut honey had a significant effect on the morning blood sugar level, which decreased for every participant in the group (15 people). The average blood sugar level at the beginning in the walnut group was 4.81 mmol L, whereas the value after 21 days was 3.73 mmol L. The total decrease level of the individuals was about 22.45% (1.08 mmol L). Concerning the sea buckthorn and chlorella alga-based honey product groups, there was no significant change in the blood sugar level, which were recorded at 4.91 and 5.28 mmol L before treatment and 5.28 and 5.07 mmol L after, respectively. In the case of the acacia honey group, there was a slight significant decrease as well, it was 4.77 mmol L at the beginning and 4.27 mmol L at the end with a total decrease rate of 10.48%. It could thus be concluded that the active ingredients of green walnut can significantly decrease the blood sugar level in humans. This study, as a first report, is not only a new innovative process to add herbs or healthy active ingredients to honey but also shows how these beneficial ingredients aid the honey in controlling the human blood sugar level.
人体血糖水平很重要,应加以控制,以避免对神经和血管造成任何损害,而这可能导致心脏病和许多其他问题。可以使用几种市面上可买到的糖尿病治疗方法,如胰岛素疗法、合成药物、草药和透皮贴剂,来帮助控制血糖。在一项双盲人体研究中,用取自以金合欢、沙棘、小球藻和青皮核桃提取物为食的蜜蜂所产的四种蜂蜜强化酸奶,用于控制人体血糖。在一项有60名参与者的人体研究中,研究了一种先前强化过的蜂蜜对健康个体的血糖水平和其他参数的影响。参与者每天早上食用150毫升混合了30克蜂蜜的酸奶,持续21天。在研究期前后,检测基本血液参数,参与者填写标准化的自我报告问卷。金合欢蜂蜜是用作对照的传统蜂蜜;特殊蜂蜜产品是通过专利技术生产的。食用青皮核桃蜂蜜对早晨血糖水平有显著影响,该组(15人)的每位参与者血糖水平均下降。核桃组开始时的平均血糖水平为4.81毫摩尔/升,而21天后的值为3.73毫摩尔/升。个体的总体下降水平约为22.45%(1.08毫摩尔/升)。关于沙棘和小球藻基蜂蜜产品组,血糖水平没有显著变化,治疗前分别记录为4.91和5.28毫摩尔/升,治疗后分别为5.28和5.07毫摩尔/升。在金合欢蜂蜜组中,也有轻微的显著下降,开始时为4.77毫摩尔/升,结束时为4.27毫摩尔/升,总下降率为10.48%。因此可以得出结论,青皮核桃的活性成分可以显著降低人体血糖水平。这项研究作为首次报告,不仅是一种将草药或健康活性成分添加到蜂蜜中的全新创新工艺,还展示了这些有益成分如何帮助蜂蜜控制人体血糖水平。