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藻类多糖的治疗应用前景

Perspective on the Therapeutic Applications of Algal Polysaccharides.

作者信息

Nigam Sonal, Singh Rachana, Bhardwaj Sheetal Kaushik, Sami Rokkayya, Nikolova Maria P, Chavali Murthy, Sinha Surbhi

机构信息

Amity Institute of Microbial Technology, Amity University, Sector 125, Noida, 201 313 Uttar Pradesh India.

Amity Institute of Biotechnology, Amity University, Sector 125, Noida, 201313 Uttar Pradesh India.

出版信息

J Polym Environ. 2022;30(3):785-809. doi: 10.1007/s10924-021-02231-1. Epub 2021 Jul 20.

DOI:10.1007/s10924-021-02231-1
PMID:34305487
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8294233/
Abstract

ABSTRACT

Algae are an enormous source of polysaccharides and have gained much interest in human flourishing as organic drugs. Algal polysaccharides have aroused interest in the health sector owing to the various bioactivities namely anticancer, antiviral, immunoregulation, antidiabetic and antioxidant effects. The research community has comprehensively described the importance of algal polysaccharides regarding their extraction, purification, and potential use in various sectors. However, regardless of all the intriguing properties and potency in the health sector, these algal polysaccharides deserve detailed investigation. Hence, the present review emphasizes extensively on the previous and latest developments in the extraction, purification, structural properties and therapeutic bioactivities of algal polysaccharides to upgrade the knowledge for further advancement in this area of research. Moreover, the review also addresses the challenges, prospective research gaps and future perspective. We believe this review can provide a boost to upgrade the traditional methods of algal polysaccharide production for the development of efficacious drugs that will promote human welfare.

摘要

摘要

藻类是多糖的巨大来源,作为有机药物在人类健康领域备受关注。藻类多糖因其抗癌、抗病毒、免疫调节、抗糖尿病和抗氧化等多种生物活性而在健康领域引起了人们的兴趣。研究界已全面描述了藻类多糖在提取、纯化以及在各个领域的潜在用途方面的重要性。然而,尽管藻类多糖在健康领域具有所有这些引人入胜的特性和潜力,但仍值得进行详细研究。因此,本综述广泛强调了藻类多糖在提取、纯化、结构特性和治疗生物活性方面的先前和最新进展,以提升该研究领域进一步发展的知识。此外,该综述还讨论了挑战、潜在的研究空白和未来展望。我们相信,这篇综述能够推动藻类多糖生产传统方法的升级,以开发促进人类福祉的有效药物。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/713f/8294233/f086cb55e100/10924_2021_2231_Fig8_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/713f/8294233/815939c5e932/10924_2021_2231_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/713f/8294233/74c9afde2aec/10924_2021_2231_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/713f/8294233/2fd2aec5a71e/10924_2021_2231_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/713f/8294233/481caf3826dc/10924_2021_2231_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/713f/8294233/1fa3fef4e6ae/10924_2021_2231_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/713f/8294233/2229b404ce13/10924_2021_2231_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/713f/8294233/d36788bb01e3/10924_2021_2231_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/713f/8294233/f086cb55e100/10924_2021_2231_Fig8_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/713f/8294233/815939c5e932/10924_2021_2231_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/713f/8294233/74c9afde2aec/10924_2021_2231_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/713f/8294233/2fd2aec5a71e/10924_2021_2231_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/713f/8294233/481caf3826dc/10924_2021_2231_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/713f/8294233/1fa3fef4e6ae/10924_2021_2231_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/713f/8294233/2229b404ce13/10924_2021_2231_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/713f/8294233/d36788bb01e3/10924_2021_2231_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/713f/8294233/f086cb55e100/10924_2021_2231_Fig8_HTML.jpg

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