Tripathy Bichitrananda, Sahoo Nityananda, Sahoo Sudhir Kumar
Centurion University of Technology & Management, Odisha, 752050, India.
Royal College of Pharmacy and Health Sciences, Berhampur, Odisha, 759024, India.
Biocatal Agric Biotechnol. 2021 May;33:102014. doi: 10.1016/j.bcab.2021.102014. Epub 2021 Apr 30.
Diabetic mellitus (DM) is a common metabolic disorder prevailing throughout the world. It may affect a child to an older person depending upon the physiology and the factors influencing the internal metabolic system of the body. Several treatments are available in the market ranges from synthetic drugs, insulin therapy, herbal drugs, and transdermal patches. Interestingly, the development of technologies and digital health have proving very helpful in improving the lifestyle of diabetic patients. All treatment approaches have their own advantages and disadvantages in the form of effectiveness and side effects. Medicinal plants have a long history of traditional application in the treatment of diabetes and even the use of plants are growing day-by-day due to the significant results against diseases and fewer side effects as compared to other treatment therapies. The intention behind writing this review is to gather all information and discussed them exhaustively in an article. The novel Coronavirus 2019 (COVID-19) pandemic has affected my lives including diabetic patients. The antidiabetic treatment strategies during this period has also discussed. In this article, we highlighted the molecular mechanism and herbal phytoconstituents that are responsible for lowering blood glucose level. The factors responsible for the progression of metabolic disorders can be controlled with the use of phytoconstituents present in herbal plants to maintain β-cells performance and restore blood glucose level. It can be concluded that medicinal plants are effective and affordable with lesser side effects for treating DM.
糖尿病（DM）是一种在全球普遍存在的常见代谢紊乱疾病。它可能影响从儿童到老年人的各个年龄段人群，这取决于生理状况以及影响人体内部代谢系统的因素。市场上有多种治疗方法，包括合成药物、胰岛素疗法、草药和透皮贴剂。有趣的是，技术和数字健康的发展已证明对改善糖尿病患者的生活方式非常有帮助。所有治疗方法在有效性和副作用方面都有其自身的优缺点。药用植物在治疗糖尿病方面有着悠久的传统应用历史，而且由于与其他治疗方法相比，其对疾病有显著疗效且副作用较少，植物的使用也日益增多。撰写本综述的目的是收集所有信息并在一篇文章中进行详尽讨论。2019年新型冠状病毒（COVID - 19）大流行已经影响了包括糖尿病患者在内的人们的生活。在此期间的抗糖尿病治疗策略也进行了讨论。在本文中，我们重点介绍了负责降低血糖水平的分子机制和草药植物成分。通过使用草药植物中存在的植物成分来维持β细胞功能并恢复血糖水平，可以控制导致代谢紊乱进展的因素。可以得出结论，药用植物治疗糖尿病有效且价格低廉，副作用较小。
