Department of Food Science and Technology, School of Agriculture and Biology, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai, 200240, China.
Department of Food Science and Technology, School of Agriculture and Biology, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai, 200240, China; Key Laboratory of Urban Agriculture (South), Ministry of Agriculture, 800 Dongchuan Road, Shanghai, 200240, China.
J Dairy Sci. 2022 Aug;105(8):6536-6547. doi: 10.3168/jds.2021-21438. Epub 2022 Jun 7.
Dairy products, characterized by rich nutrition and unique flavor, occupy an increasing share of the human diet with the development of higher living standards. However, trace hazardous contaminants in dairy products, such as polycyclic aromatic hydrocarbons (PAH), are arousing public concern. In this study, we investigated 82 milks and milk powders from Shanghai markets for the occurrence of 20 PAH, including 16 European Union priority (EU 15+1) PAH and 4 derivatives. Furthermore, we carried out a risk assessment of dietary exposure of PAHs from dairy products based on detection results and data on body weight and dietary intake obtained from questionnaires. Two assessment methods were used in this study: the incremental lifetime cancer risk (ILCR) and margin of exposure (MOE) methods. The ILCR of all age groups was 10 to 10, indicating a potential but acceptable carcinogenic risk. The MOE of the 4 groups (divided by age and sex) was >10, indicating no significant carcinogenic risk of PAH exposure from dairy products. In both methods, children had the highest risk because of their greater consumption of dairy products, followed by seniors, young adults, and middle-aged adults. Results of this study provide reference data on the exposure level and health risk of PAHs from dairy product intake.
乳制品以其丰富的营养和独特的风味，随着生活水平的提高，在人类饮食中所占份额不断增加。然而，乳制品中痕量的有害污染物，如多环芳烃（PAH），引起了公众的关注。本研究对上海市场上的 82 种牛奶和奶粉中的 20 种 PAH 进行了检测，包括欧盟优先 15+1 种 PAH 和 4 种衍生物。此外，我们根据检测结果和问卷调查得到的体重和饮食摄入量数据，对来自乳制品的 PAHs 的膳食暴露进行了风险评估。本研究采用了两种评估方法：增量终生癌症风险（ILCR）和暴露边际（MOE）方法。所有年龄段的 ILCR 均为 10 到 10，表明存在潜在但可接受的致癌风险。4 个组（按年龄和性别划分）的 MOE ＞10，表明从乳制品中摄入 PAH 不存在显著的致癌风险。在这两种方法中，儿童由于摄入更多的乳制品，风险最高，其次是老年人、年轻人和中年人。本研究结果为乳制品中 PAH 暴露的水平和健康风险提供了参考数据。
