Department of Evidence-Based Medicine, Centro Universitário Lusíada, Santos, Brazil.
Department of Gastroenterology, Universidade de São Paulo, São Paulo, Brazil.
J Surg Oncol. 2022 Jul;126(1):76-89. doi: 10.1002/jso.26857.
This study aims to estimate whether prophylactic cervical lymphadenectomy for esophageal cancer influences the short- and long-term results through a systematic literature review and meta-analysis. Twenty-eight articles were selected in this systematic review, encompassing 9180 patients. Prophylactic neck lymphadenectomy for esophageal cancer should be performed with caution, as it is associated with worse short-term results compared to traditional two-field lymphadenectomy and does not improve long-term survival.
本研究旨在通过系统文献回顾和荟萃分析来评估预防性颈淋巴结清扫术对食管癌的短期和长期结果是否有影响。本系统综述共选择了 28 篇文章，涵盖了 9180 名患者。预防性颈淋巴结清扫术在食管癌中的应用应慎重，因为与传统的二野淋巴结清扫术相比，其短期效果较差，且不能改善长期生存率。
