Department of Neuroscience, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Department of Neuroscience, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Trends Neurosci. 2022 Sep;45(9):649-650. doi: 10.1016/j.tins.2022.05.009. Epub 2022 Jun 8.
In a recent study, Bolkan, Stone, and colleagues demonstrated that direct and indirect striatal pathways in mice exert opponent control over choice behavior in a task- and state-dependent manner. This work highlights the need for rigorously controlled behavioral experiments and novel behavioral modeling in investigations of the neural mechanisms of decision making.
在最近的一项研究中,Bolkan、Stone 和同事们证明了在任务和状态依赖的方式下,小鼠的直接和间接纹状体通路对选择行为进行了对手控制。这项工作强调了在研究决策的神经机制时,需要进行严格控制的行为实验和新的行为建模。