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比率荧光传感与逻辑运算:原理、设计与应用。

Ratiometric fluorescence sensing with logical operation: Theory, design and applications.

机构信息

College of Chemistry and Enviromental Science, Inner Mongolia Key Laboratory of Environmental Chemistry, Inner Mongolia Normal University, 81 zhaowudalu, Hohhot, 010022, China.

College of Pharmacy, Inner Mongolia Medical University, Jinchuankaifaqu, Hohhot, 010110, China.

出版信息

Biosens Bioelectron. 2022 Oct 1;213:114456. doi: 10.1016/j.bios.2022.114456. Epub 2022 Jun 7.

DOI:10.1016/j.bios.2022.114456
PMID:35691083
Abstract

The construction of ratiometric fluorescence sensing logic systems has gradually become a hot topic in fluorescence analysis, due to the multi-target analysis potential of logic operations and the high specificity and selectivity of ratiometric fluorescence sensing. In this paper, the basic principles of various logic functions implemented in ratiometric fluorescence detection are discussed in the context of sensing mechanisms, and the strategies for constructing logic systems in different ratiometric fluorescence sensing application areas are summarized. Although there are limitations such as cumbersome operations and complicated experiments, ratiometric fluorescence sensing logic circuits that combine the visualization of logic operations and the accuracy of ratiometric fluorescence are still worthy of in-depth study. This review may be useful for researchers interested in the construction of logic operations based on ratiometric fluorescence sensing applications.

摘要

比率荧光传感逻辑系统的构建由于逻辑运算的多目标分析潜力和比率荧光传感的高特异性和选择性,逐渐成为荧光分析的热门话题。本文从传感机制的角度讨论了在比率荧光检测中实现各种逻辑功能的基本原理,并总结了在不同比率荧光传感应用领域构建逻辑系统的策略。尽管存在操作繁琐、实验复杂等局限性,但将逻辑运算的可视化和比率荧光的准确性相结合的比率荧光传感逻辑电路仍然值得深入研究。本文综述可能对有兴趣构建基于比率荧光传感应用的逻辑运算的研究人员有用。

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