Asbestos and renal adenocarcinoma: a case-control study.

A case-control study of renal adenocarcinoma has corroborated the hypothesis that asbestos is a cause of the disease. The odds of having been moderately or heavily exposed to asbestos 30 years before diagnosis were 45:473 among cases, whereas the comparable odds among controls were 26:492. A matched-pair analysis yielded an exposure odds ratio of 1.8 with 95% confidence limits of 1.1 and 3.1. After controlling for potential confounders and selection factors by means of logistic regression, the incidence rate ratio was estimated to be 1.6, with a one-sided 95% confidence limit of 1.0.