Gansu Provincial Center for Disease Control and Prevention, Lanzhou, China.
State Key Laboratory of Infectious Disease Prevention and Control, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
Front Public Health. 2022 May 26;10:910872. doi: 10.3389/fpubh.2022.910872. eCollection 2022.
The Qinghai-Tibet Plateau is considered the most plague-heavy region in China, and skinning and eating marmots () are understood to be the main exposure factors to plague. is relatively inactive during marmots' hibernation period. However, this case report shows plague infection risk is not reduced but rather increased during the marmot hibernation period if plague exposure is not brought under control.
The patient was a 45-year-old man who presented with high fever, swelling of axillary lymph nodes, and existing hand wounds on his right side. was isolated from his blood and lymphatic fluid. Hence, the patient was diagnosed with a confirmed case of bubonic plague. Later, his condition progressed to septicemic plague. Plague exposure through wounds and delays in appropriate treatment might have contributed to plague progression.
This case report reveals that excavating a hibernating marmot is a significant transmission route of plague. Plague prevention and control measures are priority needs during the marmot hibernation period.
青藏高原被认为是中国鼠疫最严重的地区,剥食旱獭被认为是感染鼠疫的主要暴露因素。在旱獭冬眠期间,跳蚤相对不活跃。然而,本病例报告显示,如果不控制鼠疫暴露,在旱獭冬眠期间感染鼠疫的风险不仅没有降低,反而增加。
患者为 45 岁男性,表现为高热、腋窝淋巴结肿大,右侧手部存在伤口。从其血液和淋巴液中分离出了。因此,患者被诊断为确诊的腺鼠疫病例。随后,他的病情进展为败血型鼠疫。鼠疫通过伤口暴露和延迟适当治疗可能导致鼠疫的进展。
本病例报告揭示了挖掘冬眠旱獭是鼠疫的重要传播途径。在旱獭冬眠期间,鼠疫的预防和控制措施是当务之急。