Yin Shan, Cui Yanyan, Jiao Wanzhen, Zhao Bojun
The First Clinical Medical College, Shandong University of Traditional Chinese Medicine, Jinan, China.
Department of Ophthalmology, Liaocheng People's Hospital, Liaocheng, China.
Front Med (Lausanne). 2022 May 25;9:839082. doi: 10.3389/fmed.2022.839082. eCollection 2022.
The second most prevalent cause of retinal vascular disease is retinal vein occlusion (RVO). RVO raises intravascular pressure in the capillary and veins, triggering vessel barrier collapse and subsequent leaking of blood or plasma components into the tissue (edema). Macular edema (ME) is a major complication of RVO that results in significant visual impairment. Laser therapy, intravitreal steroid injections, and vascular endothelial growth factor (VEGF) inhibitors are the major therapeutic techniques. Different therapies reduce ME of RVO and improve visual activity. However, some people have no impact on the resolution of ME, while others have a poor visual prognosis despite full ME cure. There are many investigators who studied the relationship between indicators of various instruments with visual activity. However, a summary of those findings is currently lacking. Therefore, we will focus on the predictive factors of different studies associated with positive visual activity outcomes, which would be very useful and important to help address both treatment expectations and methods for patients with RVO.
视网膜血管疾病的第二大常见病因是视网膜静脉阻塞（RVO）。RVO会升高毛细血管和静脉内的血管压力，引发血管屏障崩溃，随后血液或血浆成分渗漏到组织中（水肿）。黄斑水肿（ME）是RVO的一种主要并发症，会导致严重的视力损害。激光治疗、玻璃体内注射类固醇和血管内皮生长因子（VEGF）抑制剂是主要的治疗技术。不同的疗法可减轻RVO的ME并改善视觉活动。然而，有些人对ME的消退没有影响，而另一些人尽管ME完全治愈，但视力预后却很差。有许多研究人员研究了各种仪器指标与视觉活动之间的关系。然而，目前缺乏对这些研究结果的总结。因此，我们将重点关注与积极视觉活动结果相关的不同研究的预测因素，这对于帮助解决RVO患者的治疗期望和方法非常有用且重要。
