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人参基因组数据库:一个用于……的综合平台 (你提供的原文不完整,翻译可能不太准确,你可补充完整原文后再让我翻译)

PanaxGDB: A Comprehensive Platform for .

作者信息

Lin Yuan, Hao Bing, Lu Ying Chun, Dong Yang, Li Ying, Zhang Guang Hui, Yang Zi Jiang, Xiang Gui Sheng, Liu Guan Ze, Li Xue Jiao, Zhu Qin, Yang Qing Hui, Li Xu Zhen, Yang Sheng Chao

机构信息

State Key Laboratory of Conservation and Utilization of Bio-Resources in Yunnan, The Key Laboratory of Medicinal Plant Biology of Yunnan Province, National & Local Joint Engineering Research Center on Germplasms Innovation & Utilization of Chinese Medicinal Materials in Southwest China, Yunnan Agricultural University, Kunming, China.

Key Laboratory of Medicinal Plant Biology, Yunnan Agricultural University, Kunming, China.

出版信息

Front Plant Sci. 2022 May 25;13:883818. doi: 10.3389/fpls.2022.883818. eCollection 2022.

Abstract

The genus is a valuable natural medicinal source used worldwide that contains high levels of triterpenoid saponins with extensive pharmacological activities. In past decades, molecular biotechnology and breeding techniques have been respectively used to generate omics data and information on cultivars primarily from (ginseng), (American ginseng), and (Sanqi) to biosynthesize valuable saponins, improve product quality, and conduct cost-controlled cultivation. Although much data have been produced, there are concerns that redundant data might be generated and that relatively scattered data might be overlooked. Therefore, many scientists desire a reliable, comprehensive omics database of the genus that could save time and promote integrated analysis. Therefore, to provide all-inclusive, reliable, and valuable information on the genus, PanaxGDB, an open comprehensive database that integrates data on omics and information on varieties, was established. The database contains information on nearly 600 compounds from 12 species, draft genomic sequences with annotations and gene expression levels, single nucleotide polymorphisms, genome-wide association analysis based on agronomic traits, globally collected germplasm information, summaries, omics data of the genus, and online versatile analytic tools. The genus database will be updated when new data are released to continue serving as a central portal to boost research on the biology and functions of . PanaxGDB is available at: http://panaxGDB.ynau.edu.cn.

摘要

该属是一种在全球范围内使用的珍贵天然药用资源,含有高水平的三萜皂苷,具有广泛的药理活性。在过去几十年中,分子生物技术和育种技术分别被用于生成主要来自人参、西洋参和三七的品种的组学数据和信息,以生物合成有价值的皂苷、提高产品质量并进行成本可控的种植。尽管已经产生了大量数据,但人们担心可能会产生冗余数据,并且相对分散的数据可能会被忽视。因此,许多科学家希望有一个可靠、全面的该属组学数据库,以节省时间并促进综合分析。因此,为了提供关于该属的全面、可靠和有价值的信息,建立了PanaxGDB,一个整合组学数据和品种信息的开放综合数据库。该数据库包含来自12种人参属植物的近600种化合物的信息、带有注释和基因表达水平的基因组序列草图、单核苷酸多态性、基于农艺性状的全基因组关联分析、全球收集的种质信息、人参属组学数据总结以及在线通用分析工具。当有新数据发布时,人参属数据库将进行更新,继续作为一个核心门户,推动对人参生物学和功能的研究。PanaxGDB可通过以下网址访问:http://panaxGDB.ynau.edu.cn。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8715/9174995/b9c7af417520/fpls-13-883818-g0001.jpg

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