University of Wisconsin-Madison School of Medicine and Public Health, Department of Medical Physics, USA.
TrisKem International, France.
Appl Radiat Isot. 2022 Sep;187:110307. doi: 10.1016/j.apradiso.2022.110307. Epub 2022 May 28.
Increasing interest in targeted radionuclide therapy motivates the development of new radionuclides. The unique emission spectrum from Ge make it an ideal candidate for probing microdosimetric effects of low energy electrons absent confounding photon dose. This work reports a novel intermetallic target of Co and Ga for accelerator production of no-carrier-added Ge and a new method to isolate the Ge in high yields and purities.
人们对靶向放射性核素治疗的兴趣日益浓厚,这推动了新放射性核素的发展。锗独特的发射光谱使其成为探测低能电子微剂量效应的理想候选物,而不会受到混杂光子剂量的影响。本工作报道了一种用于加速器生产无载体添加锗的新型 Co 和 Ga 金属间化合物靶材,以及一种从靶材中高效高纯度分离锗的新方法。