Freelance Journalist, Berlin, Germany.
Biomed J. 2022 Jun;45(3):427-431. doi: 10.1016/j.bj.2022.06.001. Epub 2022 Jun 10.
In this issue of Biomedical Journal we encounter the chemokine superfamily and its clinical potential. The time course from 56 days zero COVID-19 to a resurgence in cases is presented, as well as a possible solution to overcome rejection in vascularized composite allotransplantation. We are shown the opportunity deep learning (DL) offers in the case of tracking single cells and particles, and also use of DL to bring all hands on deck to counter the current challenge of the COVID-19 pandemic. This issue contains articles about the effect of low energy shock waves in cystitis; the negative effect of high fructose on aortic valve stenosis; a study about the outcome of fecal microbiota transplantation in case of refractory Clostridioides difficile infection; a novel long non-coding RNA that could serve in treating triple-negative breast cancer; the benefits of acupressure in patients with restless leg syndrome; and Filamin A mutations in abnormal neuronal migration development. Finally, a link between jaw surgery and the psychological impact on the patient is explored; a method presented that allows identification of cervical characteristics associated with difficult embryo transfer; and a letter suggesting new parameters to evaluate the use of bone-substitute augmentation in the treatment of osteoporotic intertrochanteric fractures.
在本期《生物医学期刊》中,我们遇到了趋化因子超家族及其临床潜力。文中介绍了从 56 天无 COVID-19 到病例再次激增的时间过程,以及克服血管化复合组织同种异体移植排斥反应的可能解决方案。我们展示了深度学习(DL)在跟踪单细胞和颗粒方面的机会,以及使用 DL 来调动所有力量来应对当前 COVID-19 大流行的挑战。本期包含了关于低能量冲击波在膀胱炎中的作用、高果糖对主动脉瓣狭窄的负面影响、粪便微生物移植治疗难治性艰难梭菌感染结果的研究、一种可能用于治疗三阴性乳腺癌的新型长非编码 RNA、穴位按压对不安腿综合征患者的益处、异常神经元迁移发育中的细丝蛋白 A 突变的文章。最后,探讨了颌骨手术与患者心理影响之间的联系;提出了一种可以识别与胚胎移植困难相关的颈椎特征的方法;以及一封建议评估用于治疗骨质疏松性转子间骨折的骨替代物增强的新参数的信件。