Blaser J, Münch R, Lüthy R
J Antimicrob Chemother. 1987 Feb;19(2):233-8. doi: 10.1093/jac/19.2.233.
5-epi-sisomicin was given as a single intramuscular injection of 1 mg/kg to six healthy male adults. Serum peak concentrations averaged 3.07 mg/l, the mean elimination half life was 179 min and the mean 24 h urinary recovery was 85.3%. Local and systemic tolerance was good.
对6名健康成年男性单次肌肉注射1毫克/千克的5-表紫苏霉素。血清峰值浓度平均为3.07毫克/升,平均消除半衰期为179分钟,24小时平均尿回收率为85.3%。局部和全身耐受性良好。