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小脑、脑干、脊髓和马尾神经弥漫性神经型布鲁氏菌病:病例报告及文献复习。

Diffuse Neurobrucellosis of Cerebellum, Brainstem, Spinal Cord, and Cauda Equina: A case report and Literature review.

机构信息

Department of Radiology, Advanced diagnostic and interventional radiology research center (ADIR), Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran.

Department of Rheumatology, Internal Medicine, Amiralam Hospital, Tehran University of Medical Sciences, Tehran, Iran.

出版信息

J Radiol Case Rep. 2022 May 1;16(5):1-9. doi: 10.3941/jrcr.v16i5.3960. eCollection 2022 May.

DOI:10.3941/jrcr.v16i5.3960
PMID:35711686
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9165610/
Abstract

Neurobrucellosis is an uncommon serious complication of brucellosis. Diagnosis of neurobrucellosis could be difficult due to non-specific clinical and radiological findings. So, in endemic regions, neurobrucellosis should be included in the differential diagnosis list of patients with recent neurological disorders. We report an unusual case of neurobrucellosis with neurologic deficits in the central and peripheral nervous system and MRI lesions in the brainstem, spinal cord, and nerve roots Also, related articles are reviewed in the discussion section.

摘要

神经型布鲁氏菌病是布鲁氏菌病少见的严重并发症。由于临床表现和影像学检查无特异性,神经型布鲁氏菌病的诊断较为困难。因此,在流行地区,对于有近期神经系统疾病的患者,应将神经型布鲁氏菌病纳入鉴别诊断。我们报告了一例不常见的神经型布鲁氏菌病病例,该患者有中枢和周围神经系统神经功能缺损,并伴有脑干、脊髓和神经根的 MRI 病变。在讨论部分还回顾了相关文献。

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Pol J Radiol. 2025 Apr 3;90:e161-e169. doi: 10.5114/pjr/200911. eCollection 2025.
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The research trend on neurobrucellosis over the past 30 years (1993-2023): a bibliometric and visualization analysis.过去30年(1993 - 2023年)神经型布鲁氏菌病的研究趋势:文献计量学与可视化分析
Front Neurol. 2024 Sep 23;15:1349530. doi: 10.3389/fneur.2024.1349530. eCollection 2024.
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Case report: A case of abrupt stroke as the first symptom of neurobrucellosis.病例报告:一例以突发卒中为神经型布鲁氏菌病首发症状的病例。
Front Neurol. 2023 Feb 22;14:1066042. doi: 10.3389/fneur.2023.1066042. eCollection 2023.

本文引用的文献

1
Neurobrucellosis in a 9-year-old girl.一名9岁女孩的神经型布鲁氏菌病
J Radiol Case Rep. 2019 Dec 31;13(12):13-19. doi: 10.3941/jrcr.v13i12.3734. eCollection 2019 Dec.
2
Neurobrucellosis with intramedullary spinal cord involvement: A case report.伴有脊髓受累的神经型布鲁氏菌病:一例报告。
Iran J Neurol. 2018 Jul 6;17(3):152-153.
3
Treatment Efficacy and Risk Factors of Neurobrucellosis.神经型布鲁氏菌病的治疗效果及危险因素
Med Sci Monit. 2016 Mar 28;22:1005-12. doi: 10.12659/msm.897947.
4
A extremely rare case of cervical intramedullary granuloma due to Brucella accompanied by Chiari Type-1 malformation.一例极为罕见的由布鲁氏菌引起的伴有Chiari I型畸形的颈段脊髓内肉芽肿病例。
Asian J Neurosurg. 2014 Jul-Sep;9(3):173-6. doi: 10.4103/1793-5482.142740.
5
An unusual case of neurobrucellosis presenting as demyelination disorder.一例表现为脱髓鞘疾病的罕见神经型布鲁氏菌病病例。
Turk J Pediatr. 2013 Mar-Apr;55(2):210-3.
6
Neurobrucellosis: clinical, diagnostic, therapeutic features and outcome. Unusual clinical presentations in an endemic region.神经布鲁菌病:临床、诊断、治疗特点和结果。流行地区的不典型临床表现。
Braz J Infect Dis. 2011 Jan-Feb;15(1):52-9.
7
[The value of culture and serological methods in the diagnosis of human brucellosis].[文化和血清学方法在人类布鲁氏菌病诊断中的价值]
Mikrobiyol Bul. 2008 Jan;42(1):185-95.
8
Clinical and laboratory findings in neurobrucellosis: review of 31 cases.神经型布鲁氏菌病的临床与实验室检查结果:31例病例回顾
Arch Iran Med. 2008 Jan;11(1):21-5.
9
The new global map of human brucellosis.人类布鲁氏菌病的新全球地图。
Lancet Infect Dis. 2006 Feb;6(2):91-9. doi: 10.1016/S1473-3099(06)70382-6.
10
Comparison of three different combination therapies in the treatment of human brucellosis.三种不同联合疗法治疗人类布鲁氏菌病的比较
Trop Doct. 2005 Oct;35(4):210-2. doi: 10.1258/004947505774938765.