Hagberg Guri, Ihle-Hansen Håkon, Sandset Else Charlotte, Jacobsen Dag, Wimmer Henning, Ihle-Hansen Hege
Department of Medical Research, Baerum Hospital Vestre Viken Hospital Trust, Drammen, Norway.
Oslo Stroke Unit, Department of Neurology, Oslo University Hospital, Ullevål, Norway.
Front Aging Neurosci. 2022 May 26;14:885226. doi: 10.3389/fnagi.2022.885226. eCollection 2022.
Out-of-hospital cardiac arrest (OHCA) is a leading cause of mortality worldwide. With better pre- and inhospital treatment, including cardiopulmonary resuscitation (CPR) as an integrated part of public education and more public-access defibrillators available, OHCA survival has increased over the last decade. There are concerns, after successful resuscitation, of cerebral hypoxia and degrees of potential acquired brain injury with resulting poor cognitive functioning. Cognitive function is not routinely assessed in OHCA survivors, and there is a lack of consensus on screening methods for cognitive changes. This narrative mini-review, explores available evidence on hypoxic brain injury and long-term cognitive function in cardiac arrest survivors and highlights remaining knowledge deficits.
院外心脏骤停（OHCA）是全球主要的死亡原因。随着院前和院内治疗的改善，包括将心肺复苏（CPR）作为公众教育的一个组成部分以及更多公共场所配备自动体外除颤器，OHCA的生存率在过去十年有所提高。在成功复苏后，人们担心会出现脑缺氧以及潜在的后天性脑损伤程度，进而导致认知功能不佳。OHCA幸存者通常不会接受认知功能评估，而且对于认知变化的筛查方法也缺乏共识。这篇叙述性小型综述探讨了心脏骤停幸存者缺氧性脑损伤和长期认知功能的现有证据，并突出了尚存的知识空白。
