Janssen I
J Math Biol. 1987;24(6):681-9. doi: 10.1007/BF00275510.
The purpose of this paper is to present a stochastic model for effects of radiation on cells. The model includes provisions for lethal effects and for transformation to malignant status. Empirical findings indicate the presence of some repair mechanism in the cells, and a way to incorporate this idea into the model is discussed. Comparisons of the derived survival and transformation probabilities with actual data are favorable. The interpretation of the estimated values leads to questions to be investigated by the experimenters.
本文的目的是提出一个关于辐射对细胞影响的随机模型。该模型包括了致死效应和细胞转化为恶性状态的相关内容。实证研究结果表明细胞中存在某种修复机制，并讨论了将这一观点纳入模型的方法。将推导得出的存活概率和转化概率与实际数据进行比较，结果令人满意。对估计值的解释引发了一些有待实验人员研究的问题。
