From the Bioanalytics Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Morgantown, West Virginia (Gu, Dr Charles, Dr Allison, Dr Andrew); Department of Epidemiology and Environmental Health, School of Public Health and Health Professions, State University of New York at Buffalo, Buffalo, New York (Dr Violanti).
J Occup Environ Med. 2022 Sep 1;64(9):748-753. doi: 10.1097/JOM.0000000000002569. Epub 2022 Jun 21.
OBJECTIVES: We examined the associations of the metabolic syndrome severity score (MSSS) and the metabolic syndrome (MetSyn) components with central retinal arteriolar equivalent (CRAE) and central retinal venular equivalent (CRVE). METHODS: Participants in this cross-sectional study were 253 officers from the Buffalo Cardio-Metabolic Occupational Police Stress study (2011-2014). The MSSS is a z -score that represents the severity of MetSyn and was estimated using a sex/race-specific equation and the five MetSyn components. Associations of MSSS and the MetSyn with CRAE/CRVE were obtained using linear regression models or analysis of covariance. RESULTS: For every 1-standard deviation of MSSS, CRAE decreased by 2.3 μm (SE = 1.2, P = 0.0262) and CRVE increased by 3.4 μm (SE = 1.6, P = 0.0308) after adjusting for confounders. CONCLUSIONS: Officers with higher MSSS had narrower (ie, worse) arteriolar diameters and wider (ie, worse) venular diameters.
目的：我们研究了代谢综合征严重程度评分（MSSS）和代谢综合征（MetSyn）成分与视网膜中央动脉等效直径（CRAE）和视网膜中央静脉等效直径（CRVE）之间的关联。
方法：本横断面研究的参与者是布法罗心脏代谢职业警察应激研究（2011-2014 年）中的 253 名警官。MSSS 是一种 z 分数，代表 MetSyn 的严重程度，使用性别/种族特异性方程和五个 MetSyn 成分进行估计。使用线性回归模型或协方差分析获得 MSSS 和 MetSyn 与 CRAE/CRVE 的关联。
结果：在校正混杂因素后，MSSS 每增加 1 个标准差，CRAE 减少 2.3μm（SE=1.2，P=0.0262），CRVE 增加 3.4μm（SE=1.6，P=0.0308）。
结论：MSSS 较高的警官其动脉直径更窄（即更差），静脉直径更宽（即更差）。
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