Biostatistics and Epidemiology Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Morgantown, West Virginia (Dr Charles, Mr Gu, Ms Ma, Ms Mnatsakanova, Dr Andrew, Dr Fekedulegn); Department of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, Wisconsin (Ms Grady, Dr Klein); Department of Epidemiology and Environmental Health, School of Public Health and Health Professions, State University of New York at Buffalo, Buffalo, New York (Dr Violanti).
J Occup Environ Med. 2017 Oct;59(10):e172-e179. doi: 10.1097/JOM.0000000000001136.
To investigate associations of central retinal arteriolar equivalent (CRAE), a measure of retinal arteriolar width, and central retinal venular equivalents (CRVE), a measure of retinal venular width, with shiftwork in 199 police officers (72.9% men).
Shiftwork (day, afternoon, night) was assessed using electronic payroll records. Four digital retinal images per officer were taken. Mean diameters of the retinal vasculature were compared across shifts using analysis of variance (ANOVA)/analysis of covariance (ANCOVA).
Among all officers (mean age = 46.6 ± 6.8 years), shiftwork was not significantly associated with CRAE or CRVE. However, among current and former smokers, night-shift officers had a wider mean (±standard error [SE]) CRVE (230.0 ± 4.5 μm) compared with day shift officers (215.1 ± 3.5 μm); adjusted P = 0.014.
Night shift schedule in current and former smokers is associated with wider retinal venules. Reasons for this association are not known. Longitudinal studies are warranted.
调查中央视网膜动脉等效（CRAE），即视网膜动脉宽度的衡量标准，和中央视网膜静脉等效（CRVE），即视网膜静脉宽度的衡量标准，与 199 名警察（72.9%为男性）轮班工作的关系。
使用电子工资记录评估轮班工作（白班、下午班、夜班）。为每位警察拍摄四张数字视网膜图像。使用方差分析（ANOVA）/协方差分析（ANCOVA）比较不同班次的视网膜血管平均直径。
在所有警察（平均年龄为 46.6±6.8 岁）中，轮班工作与 CRAE 或 CRVE 没有显著关联。然而，在当前和曾经吸烟者中，夜班警察的平均（±标准误差 [SE]）CRVE（230.0±4.5μm）比白班警察宽（215.1±3.5μm）；调整后的 P 值为 0.014。
当前和曾经吸烟者的夜班轮班安排与视网膜静脉增宽有关。这种关联的原因尚不清楚。需要进行纵向研究。
