Tekassa Tamirat, Hasen Gemmechu, Merga Hailu, Cavin Anne-Laure, Graz Bertrand, Suleman Sultan
School of Pharmacy, Institute of Health, Jimma University, Jimma, Oromia Regional State, Ethiopia.
Department of Epidemiology, Institute of Health, Jimma University, Jimma, Oromia Regional State, Ethiopia.
Infect Drug Resist. 2022 Jun 16;15:3087-3095. doi: 10.2147/IDR.S367524. eCollection 2022.
With the problems of increasing levels of drug resistance and difficulties to afford and access effective antimalarial drugs in poor and remote areas, herbal medicines could be an important and sustainable source of treatment. L. (AM) is a medicinal plant known long ago in several countries for treatment of numerous diseases including malaria. The aim of this study was to conduct a survey on the use of AM in the prevention and treatment of uncomplicated malaria in selected districts of Jimma Zone, Oromia Regional state, Ethiopia.
A community-based cross-sectional study was conducted in two selected districts in Jimma Zone, southwest Ethiopia. In total, 552 participants from 17 kebeles (villages/communities) and 18 traditional healers of the districts were interviewed. Data collection was conducted from April 27 to May 18, 2020 using pre-tested structured questionnaires. The data were analyzed using Epi Info 7.0 and the descriptive statistics were used to summarize the results.
The study indicated that AM is available, known by 39.8% of the respondents and used for prevention and treatment of malaria by 5.7% of the population. All traditional healers interviewed knew the plant, and 44.4% use it for treatment of malaria. In addition, AM is especially used to treat malaria, amoebiasis, diarrhea, cough, and tuberculosis.
The availability and use of AM to treat malaria was verified in both community and traditional healers. AM, which was found effective as antimalarial plant in high endemicity in Mali, is also well known and accepted in these areas of Ethiopia for the treatment of malaria. Further research is needed to assess wether AM is also effective against malaria in Ethiopia where and coexist.
随着耐药性水平不断上升以及贫困偏远地区难以负担和获取有效的抗疟药物等问题，草药可能成为重要且可持续的治疗来源。罗芙木（A. mitis）是一种药用植物，在多个国家很早以前就被用于治疗包括疟疾在内的多种疾病。本研究的目的是对埃塞俄比亚奥罗米亚州吉马地区部分选定区域使用罗芙木预防和治疗非复杂性疟疾的情况进行调查。
在埃塞俄比亚西南部吉马地区的两个选定区域开展了一项基于社区的横断面研究。总共对来自17个村（村庄/社区）的552名参与者以及该地区的18名传统治疗师进行了访谈。2020年4月27日至5月18日期间，使用经过预测试的结构化问卷进行数据收集。使用Epi Info 7.0对数据进行分析，并使用描述性统计来总结结果。
研究表明罗芙木是可获取的，39.8%的受访者知晓该植物，5.7%的人口将其用于预防和治疗疟疾。所有接受访谈的传统治疗师都了解这种植物，44.4%的人将其用于治疗疟疾。此外，罗芙木尤其用于治疗疟疾、阿米巴病、腹泻、咳嗽和结核病。
在社区和传统治疗师中均证实了罗芙木在治疗疟疾方面的可获取性和使用情况。罗芙木在马里高流行地区被发现是一种有效的抗疟植物，在埃塞俄比亚的这些地区也广为人知并被认可用于治疗疟疾。需要进一步研究以评估在疟原虫和间日疟原虫共存的埃塞俄比亚，罗芙木对疟疾是否也有效。
