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毛茛科植物的治疗潜力:传统药草的文献综述

Therapeutic Potential of Species (Ranunculaceae): A Literature Review on Traditional Medicinal Herbs.

作者信息

Goo Youn-Kyoung

机构信息

Department of Parasitology and Tropical Medicine, School of Medicine, Kyungpook National University, Daegu 41944, Korea.

出版信息

Plants (Basel). 2022 Jun 17;11(12):1599. doi: 10.3390/plants11121599.

Abstract

The genus includes approximately 600 species and is distributed worldwide. To date, several researchers have investigated the chemical and biological activities of species, and my research team has found them to have antimalarial effects. This review is based on the available information on the traditional uses and pharmacological studies of species. The present paper covers online literature, particularly from 2010 to 2021, and books on the ethnopharmacology and botany of species. Previous studies on the biological activity of crude or purified compounds from species, including Linn., Thunb., Linn., Thunb., Linn., DC., Crantz, Linn., Rotlb., and Waldst. & Kit., have provided new insights into their activities, such as antibacterial and antiprotozoal effects as well as antioxidant, immunomodulatory, and anticarcinogenic properties. In addition, the anti-inflammatory and analgesic effects of plants used in traditional medicine applications have been confirmed. Therefore, there is a need for more diverse studies on the chemical and pharmacological activities of highly purified molecules from species extracts to understand the mechanisms underlying their activities and identify novel drug candidates.

摘要

该属包括约600个物种,分布于世界各地。迄今为止,已有几位研究人员对该属物种的化学和生物活性进行了研究,我的研究团队发现它们具有抗疟作用。本综述基于有关该属物种传统用途和药理学研究的现有信息。本文涵盖在线文献,特别是2010年至2021年的文献,以及有关该属物种民族药理学和植物学的书籍。先前对该属物种(包括Linn.、Thunb.、Linn.、Thunb.、Linn.、DC.、Crantz、Linn.、Rotlb.以及Waldst. & Kit.)的粗提物或纯化化合物生物活性的研究,为其活性提供了新的见解,如抗菌和抗原虫作用以及抗氧化、免疫调节和抗癌特性。此外,传统医学应用中使用的植物的抗炎和镇痛作用也得到了证实。因此,需要对该属物种提取物中高度纯化分子的化学和药理活性进行更多样化的研究,以了解其活性背后的机制并鉴定新的候选药物。

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