Zhang Yixin, Xiao Nong, Zhang Xilian, Zhang Zhenhua, Zhang Jiusi
Department of Rehabilitation, Children's Hospital of Chongqing Medical University, Chongqing 400010, China.
National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing 400010, China.
Brain Sci. 2022 May 27;12(6):697. doi: 10.3390/brainsci12060697.
Tic disorders are neurological disorders that are prone to fluctuation and recurrence. It is important to study the factors related to disease recurrence and to subsequently provide suggestions for clinical treatment. A retrospective study was conducted to assess patients with recurrent and non-recurring tic disorders diagnosed in the Pediatric Tic Disorder Clinic of the First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, China, and to extract various factors-such as fetal status; medication, allergy, and family history; social and psychological factors; blood lead content; electroencephalogram (EEG); disease duration; type of tics; and disease severity-and identify factors associated with recurrence. The recurrence rate of tic disorders was approximately 45.10% in this study. The childbirth conditions, surgery/trauma, respiratory tract infection, allergy, stress, consumption of tiapride, and severity of tic disorders were factors related to and affected disease recurrence.
抽动障碍是易于波动和复发的神经障碍。研究与疾病复发相关的因素并随后为临床治疗提供建议很重要。进行了一项回顾性研究，以评估在中国天津中医药大学第一附属医院儿科抽动障碍门诊诊断出的复发性和非复发性抽动障碍患者，并提取各种因素，如胎儿状况；用药、过敏和家族史；社会和心理因素；血铅含量；脑电图（EEG）；病程；抽动类型；以及疾病严重程度，并确定与复发相关的因素。在本研究中，抽动障碍的复发率约为45.10%。分娩情况、手术/创伤、呼吸道感染、过敏、压力、硫必利的使用以及抽动障碍的严重程度是与疾病复发相关并影响疾病复发的因素。
