Nazarovs Jurijs, Lapse Daira, Stūre Gunta, Soloveičika Marina, Jaunozolina Līga, Ozoliņa Elīna, Lejniece Sandra
Pathology Centre, Riga East Clinical University Hospital, Hipokrāta Street 2, LV-1038 Rīga, Latvia.
Pathology Institute, Pauls Stradins Clinical University Hospital, Pilsoņu Street 13, LV-1002 Rīga, Latvia.
Brain Sci. 2022 May 30;12(6):705. doi: 10.3390/brainsci12060705.
We present a rare case of intracranial solitary plasmacytoma arising in brain parenchyma in the basal nuclei. Clinical management and autopsy results of the case are described. Background: Intracranial plasmacytomas arising from brain parenchyma are extremely rare, and data from the literature are limited. Primary intracranial plasmacytomas are rare because plasma cells are not found in the brain in normal conditions. Commonly, intracranial plasmacytoma is associated with multiple myeloma, which is why multiple myeloma must be ruled out to diagnose solitary intracranial plasmacytoma. Considering that solitary plasmacytoma and multiple myeloma have some histopathological similarities, it is important to differentiate them because their respective treatments and prognoses are different. Imaging features of primary extramedullary plasmacytoma are nonspecific but are compatible with solid tumors with invariable enhancement. Plasmacytoma was aggressive because it was not diagnosed after the first MRI, but 1.5 months later, MRI showed a large object. We present a rare case of intracranial solitary plasmacytoma arising in brain parenchyma in the basal nuclei.
我们报告一例罕见的起源于基底核脑实质的颅内孤立性浆细胞瘤。描述了该病例的临床处理及尸检结果。背景：起源于脑实质的颅内浆细胞瘤极为罕见，文献资料有限。原发性颅内浆细胞瘤罕见，因为正常情况下脑内不存在浆细胞。通常，颅内浆细胞瘤与多发性骨髓瘤相关，这就是为何诊断孤立性颅内浆细胞瘤时必须排除多发性骨髓瘤。鉴于孤立性浆细胞瘤和多发性骨髓瘤在组织病理学上有一些相似之处，区分它们很重要，因为它们各自的治疗方法和预后不同。原发性髓外浆细胞瘤的影像学特征不具特异性，但与增强不变的实体瘤相符。浆细胞瘤具有侵袭性，因为首次MRI检查时未被诊断出来，但1.5个月后，MRI显示出一个大肿物。我们报告一例罕见的起源于基底核脑实质的颅内孤立性浆细胞瘤。
