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喂食玉米粉饼干饮食的糖尿病白鼠的血糖、血红蛋白和丙二醛水平

Blood Sugar, Haemoglobin and Malondialdehyde Levels in Diabetic White Rats Fed a Diet of Corn Flour Cookies.

作者信息

Aini Nur, Sustriawan Budi, Wahyuningsih Nadia, Mela Ervina

机构信息

Department of Food Science and Technology, Jenderal Soedirman University, Purwokerto 53123, Indonesia.

出版信息

Foods. 2022 Jun 20;11(12):1819. doi: 10.3390/foods11121819.

Abstract

The purpose of the study was to analyse the chemical composition of corn cookies containing different types of sugar and fat, and determine their effect on physiological parameters in diabetic rats. The experimental animals were studied using a randomised block design with seven groups of rats. The test groups were as follows: group 1, negative control rats (normal) fed standard; group 2, positive control rats (diabetic) fed standard; group 3, diabetic rats fed wheat cookies; group 4, diabetic rats fed C1 corn cookies; group 5, diabetic rats fed C2 corn cookies; group 6, diabetic rats fed C3 corn cookies; and group 7, diabetic rats fed C4 corn cookies. The tests on the rats revealed that the cookies had significant effects on blood sugar, malondialdehyde (MDA) and haemoglobin levels as well as body weight parameters. Corn cookies containing crystalline coconut sugar and virgin coconut oil (VCO) were effective at lowering blood sugar and MDA levels while increasing haemoglobin and body weight in diabetic rats. Significantly, after four weeks on this diet, rats with diabetes mellitus were in the same overall condition as normal rats. These findings suggest that these cookies may be gluten-free functional foods suitable for diabetics. These findings suggest that diabetics can safely consume maize cookies.

摘要

该研究的目的是分析含有不同种类糖和脂肪的玉米饼干的化学成分,并确定它们对糖尿病大鼠生理参数的影响。实验动物采用随机区组设计,分为七组大鼠。测试组如下:第1组,喂食标准饲料的阴性对照大鼠(正常);第2组,喂食标准饲料的阳性对照大鼠(糖尿病);第3组,喂食小麦饼干的糖尿病大鼠;第4组,喂食C1玉米饼干的糖尿病大鼠;第5组,喂食C2玉米饼干的糖尿病大鼠;第6组,喂食C3玉米饼干的糖尿病大鼠;第7组,喂食C4玉米饼干的糖尿病大鼠。对大鼠的测试表明,这些饼干对血糖、丙二醛(MDA)和血红蛋白水平以及体重参数有显著影响。含有结晶椰子糖和初榨椰子油(VCO)的玉米饼干在降低糖尿病大鼠血糖和MDA水平的同时,能提高血红蛋白和体重。值得注意的是,在这种饮食四周后,糖尿病大鼠的总体状况与正常大鼠相同。这些发现表明,这些饼干可能是适合糖尿病患者的无麸质功能性食品。这些发现表明糖尿病患者可以安全食用玉米饼干。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e64/9222760/1488fe516cac/foods-11-01819-g001.jpg

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