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1
Effect of tsl (thermosensitive suppressor of lex) mutation on postreplication repair in Escherichia coli K-12.tsl（lex的热敏抑制子）突变对大肠杆菌K-12中复制后修复的影响。
J Bacteriol. 1978 Sep;135(3):935-42. doi: 10.1128/jb.135.3.935-942.1978.
2
Effect of tsl mutations in decreasing radiation sensitivity of a recA- strain of Escherichia coli K-12.tsl突变对降低大肠杆菌K-12 recA-菌株辐射敏感性的影响。
J Bacteriol. 1975 Mar;121(3):1203-7. doi: 10.1128/jb.121.3.1203-1207.1975.
3
[Radioadaptive enhancement of the repair of UV-induced postreplication gaps in Escherichia coli cells deficient in DNA repair].[DNA修复缺陷的大肠杆菌细胞中紫外线诱导的复制后间隙修复的辐射适应性增强]
Tsitologiia. 2002;44(5):499-501.
4
Indirect suppression of radiation sensitivity of a recA- strain of Escherichia coli K12.
Basic Life Sci. 1975;5A:383-8. doi: 10.1007/978-1-4684-2895-7_51.
5
Suppression of lex mutations affecting deoxyribonucleic acid repair in Escherichia coli K-12 by closely linked thermosensitive mutations.通过紧密连锁的温度敏感突变抑制影响大肠杆菌K-12中脱氧核糖核酸修复的lex突变。
J Bacteriol. 1973 Nov;116(2):950-6. doi: 10.1128/jb.116.2.950-956.1973.
6
Role of DNA polymerase I in postreplication repair: a reexamination with Escherichia coli delta polA.DNA聚合酶I在复制后修复中的作用：用大肠杆菌δpolA进行的重新研究
J Bacteriol. 1987 Oct;169(10):4559-64. doi: 10.1128/jb.169.10.4559-4564.1987.
7
The dependence of postreplication repair on uvrB in a recF mutant of Escherichia coli K-12.大肠杆菌K-12的recF突变体中复制后修复对uvrB的依赖性。
Mol Gen Genet. 1977 Oct 24;155(3):279-86. doi: 10.1007/BF00272806.
8
recA (Srf) suppression of recF deficiency in the postreplication repair of UV-irradiated Escherichia coli K-12.recA（Srf）对紫外线照射的大肠杆菌K-12复制后修复中recF缺陷的抑制作用。
J Bacteriol. 1986 Nov;168(2):940-6. doi: 10.1128/jb.168.2.940-946.1986.
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Effects of chloramphenicol and caffeine on postreplication repair in uvr A- umuC- und uvrA- recF- strains of Escherichia coli K-12.氯霉素和咖啡因对大肠杆菌K-12的uvrA-umuC-及uvrA-recF-菌株中复制后修复的影响。
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10
Mechanism of sbcB-suppression of the recBC-deficiency in postreplication repair in UV-irradiated Escherichia coli K-12.紫外线照射的大肠杆菌K-12中sbcB抑制recBC缺陷在复制后修复中的机制。
Mol Gen Genet. 1985;201(2):186-91. doi: 10.1007/BF00425658.

引用本文的文献

1
Two Lactococcus lactis genes, including lacX, cooperate to trigger an SOS response in a recA-negative background.两个乳酸乳球菌基因，包括lacX，在recA阴性背景下协同触发SOS反应。
J Bacteriol. 1995 Jan;177(2):283-9. doi: 10.1128/jb.177.2.283-289.1995.
2
Regulation of the Escherichia coli K-12 uvrB operon.大肠杆菌K-12 uvrB操纵子的调控
J Bacteriol. 1982 May;150(2):676-85. doi: 10.1128/jb.150.2.676-685.1982.
3
tif-Stimulated deoxyribonucleic acid repair in Escherichia coli K-12.Tif刺激大肠杆菌K-12中的脱氧核糖核酸修复。
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4
Quantitative evaluation of recA gene expression in Escherichia coli.大肠杆菌中recA基因表达的定量评估。
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5
Effect of a lexA41(Ts) mutation on DNA repair in recA(Def) derivatives of Escherichia coli K-12.lexA41（Ts）突变对大肠杆菌K-12的recA（Def）衍生物中DNA修复的影响。
Mol Gen Genet. 1985;201(3):387-92. doi: 10.1007/BF00331328.
6
Differences in mutagenic and recombinational DNA repair in enterobacteria.肠道细菌中诱变和重组DNA修复的差异。
Proc Natl Acad Sci U S A. 1985 Jun;82(12):4172-6. doi: 10.1073/pnas.82.12.4172.

本文引用的文献

1
Three loci in Escherichia coli K-12 that control the excision of pyrimidine dimers and certain other mutagen products from DNA.大肠杆菌K-12中控制从DNA切除嘧啶二聚体和某些其他诱变产物的三个基因座。
Genetics. 1966 Jun;53(6):1119-36. doi: 10.1093/genetics/53.6.1119.
2
DNA repair and genetic recombination: studies on mutants of Escherichia coli defective in these processes.DNA修复与基因重组：对在这些过程中存在缺陷的大肠杆菌突变体的研究。
Radiat Res. 1966:Suppl 6:156+.
3
Exchanges between DNA strands in ultraviolet-irradiated Escherichia coli.紫外线照射的大肠杆菌中DNA链之间的交换
J Mol Biol. 1971 Oct 14;61(1):25-44. doi: 10.1016/0022-2836(71)90204-x.
4
Usefulness of benzoylated naphthoylated DEAE-cellulose to distinguish and fractionate double-stranded DNA bearing different extents of single-stranded regions.苯甲酰化萘甲酰化二乙氨基乙基纤维素用于区分和分离具有不同单链区域程度的双链DNA的效用。
Biochim Biophys Acta. 1971 Jan 1;228(1):117-26. doi: 10.1016/0005-2787(71)90551-x.
5
Repair of radiation-induced damage in Escherichia coli. I. Effect of rec mutations on post-replication repair of damage due to ultraviolet radiation.大肠杆菌中辐射诱导损伤的修复。I. rec突变对紫外线辐射所致损伤的复制后修复的影响。
J Mol Biol. 1970 Aug;51(3):459-72. doi: 10.1016/0022-2836(70)90001-x.
6
Discontinuities in the DNA synthesized in an excision-defective strain of Escherichia coli following ultraviolet irradiation.紫外线照射后，大肠杆菌切除缺陷菌株中合成的DNA的不连续性。
J Mol Biol. 1968 Jan 28;31(2):291-304. doi: 10.1016/0022-2836(68)90445-2.
7
DNA repair and recombination.DNA修复与重组。
Br Med Bull. 1973 Sep;29(3):226-35. doi: 10.1093/oxfordjournals.bmb.a071012.
8
Persistence of pyrimidine dimers during post-replication repair in ultraviolet light-irradiated Escherichia coli K12.紫外线照射的大肠杆菌K12在复制后修复过程中嘧啶二聚体的持续存在。
J Mol Biol. 1974 Jul 25;87(1):103-19. doi: 10.1016/0022-2836(74)90563-4.
9
Effect of photoreactivation on the filling of gaps in deoxyribonucleic acid synthesized after exposure of Escherichia coli to ultraviolet light.光复活作用对大肠杆菌经紫外线照射后合成的脱氧核糖核酸中缺口填补的影响。
J Bacteriol. 1974 Mar;117(3):1077-81. doi: 10.1128/jb.117.3.1077-1081.1974.
10
Genetic analysis of the recF pathway to genetic recombination in Escherichia coli K12: isolation and characterization of mutants.大肠杆菌K12中recF基因重组途径的遗传分析：突变体的分离与鉴定
J Mol Biol. 1973 Oct 25;80(2):327-44. doi: 10.1016/0022-2836(73)90176-9.

tsl（lex的热敏抑制子）突变对大肠杆菌K-12中复制后修复的影响。

Effect of tsl (thermosensitive suppressor of lex) mutation on postreplication repair in Escherichia coli K-12.

作者信息

Ganesan A K, Seawell P C, Mount D W

出版信息

J Bacteriol. 1978 Sep;135(3):935-42. doi: 10.1128/jb.135.3.935-942.1978.

DOI:10.1128/jb.135.3.935-942.1978
PMID:357426
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC222467/
Abstract

Cells of Escherichia coli K-12 carrying lexA or recA mutations are more sensitive to UV radiation than corresponding wild-type cells and are defective in postreplication repair. Supressor mutations (tsl) have been described previously which increase the UV resistance of lexA uvr+, lexA uvrA, and recAI uvr+ strains, but not the resistance of recA1 uvrA strains. We have studied the effect of the tsl-1 mutation on postreplication repair and find that the enhanced survival conferred by this mutation is correlated with an increased capacity for postreplication repair.

摘要

携带lexA或recA突变的大肠杆菌K-12细胞比相应的野生型细胞对紫外线辐射更敏感，并且在复制后修复方面存在缺陷。先前已经描述了抑制突变（tsl），其增加了lexA uvr +、lexA uvrA和recA1 uvr +菌株的紫外线抗性，但没有增加recA1 uvrA菌株的抗性。我们研究了tsl-1突变对复制后修复的影响，发现该突变赋予的增强存活率与复制后修复能力的增加相关。