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严重急性呼吸综合征冠状病毒2：大流行两年：我们从立陶宛的基因组测序结果中观察到了什么？

SARS-CoV-2: Two Years in the Pandemic: What Have We Observed from Genome Sequencing Results in Lithuania?

作者信息

Zemaitis Lukas, Alzbutas Gediminas, Gecyte Emilija, Gecys Dovydas, Lesauskaite Vaiva

机构信息

Laboratory of Molecular Cardiology, Institute of Cardiology, Lithuanian University of Health Sciences, LT-50162 Kaunas, Lithuania.

Laboratory of Translational Bioinformatics, Institute for Digestive Research, Lithuanian University of Health Sciences, LT-50162 Kaunas, Lithuania.

出版信息

Microorganisms. 2022 Jun 16;10(6):1229. doi: 10.3390/microorganisms10061229.

DOI:10.3390/microorganisms10061229
PMID:35744748
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9230985/
Abstract

SARS-CoV-2 has spread vastly throughout the word. In this study, we focus on the patterns of spread in Lithuania. By analysing the genetically sequenced data of different lineages and their first appearances, we were able to compare the dynamics of spreading of the lineages and recognize the main possible cause. The impact of emigration patterns and international travel on the variety of lineages was also assessed. Results showed different patterns of spread, and while a vast variety of different lineages were brought in by international travel, many of the viral outbreaks were caused by local lineages. It can be concluded that international travel had the most impact on the spread of SARS-CoV-2.

摘要

严重急性呼吸综合征冠状病毒2（SARS-CoV-2）已在全球广泛传播。在本研究中，我们聚焦于立陶宛的传播模式。通过分析不同谱系的基因测序数据及其首次出现情况，我们得以比较各谱系的传播动态并识别主要的可能原因。我们还评估了移民模式和国际旅行对谱系多样性的影响。结果显示出不同的传播模式，虽然国际旅行带来了各种各样的不同谱系，但许多病毒爆发是由本地谱系引起的。可以得出结论，国际旅行对SARS-CoV-2的传播影响最大。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c09e/9230985/956f8f7f3a8a/microorganisms-10-01229-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c09e/9230985/9fa02c1b621e/microorganisms-10-01229-g0A1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c09e/9230985/6a9740d0ebf0/microorganisms-10-01229-g0A2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c09e/9230985/33ae57216f7f/microorganisms-10-01229-g0A3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c09e/9230985/d63ede7eda70/microorganisms-10-01229-g0A4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c09e/9230985/0de74dfbb741/microorganisms-10-01229-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c09e/9230985/84be61ade682/microorganisms-10-01229-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c09e/9230985/c219d0997f70/microorganisms-10-01229-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c09e/9230985/323c3b89f13b/microorganisms-10-01229-g004a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c09e/9230985/4e98be6a7cb0/microorganisms-10-01229-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c09e/9230985/6629b348d746/microorganisms-10-01229-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c09e/9230985/956f8f7f3a8a/microorganisms-10-01229-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c09e/9230985/9fa02c1b621e/microorganisms-10-01229-g0A1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c09e/9230985/6a9740d0ebf0/microorganisms-10-01229-g0A2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c09e/9230985/33ae57216f7f/microorganisms-10-01229-g0A3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c09e/9230985/d63ede7eda70/microorganisms-10-01229-g0A4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c09e/9230985/0de74dfbb741/microorganisms-10-01229-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c09e/9230985/84be61ade682/microorganisms-10-01229-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c09e/9230985/c219d0997f70/microorganisms-10-01229-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c09e/9230985/323c3b89f13b/microorganisms-10-01229-g004a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c09e/9230985/4e98be6a7cb0/microorganisms-10-01229-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c09e/9230985/6629b348d746/microorganisms-10-01229-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c09e/9230985/956f8f7f3a8a/microorganisms-10-01229-g007.jpg

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