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脂质图谱世界之旅的花絮。

Outtakes from My Journey through the World of LIPID MAPS.

机构信息

Department of Chemistry and Biochemistry, University of California at San Diego, La Jolla, CA 92093-0601, USA.

Department of Pharmacology, School of Medicine, University of California at San Diego, La Jolla, CA 92093-0601, USA.

出版信息

Molecules. 2022 Jun 17;27(12):3885. doi: 10.3390/molecules27123885.

Abstract

My laboratory's research on lipids has focused on phospholipases and lipidomics and in many ways has evolved in parallel to the evolution of the lipid field over the past half century. I have reviewed our research elsewhere. Herein, I describe the "side stories" or "outtakes" that parallel the main story that focuses on our laboratory's research. I will emphasize the importance of community activities and describe how I came to initiate and lead the international effort on the Lipid Metabolites and Pathways Strategy (LIPID MAPS). Several of these side activities had a significant effect on discoveries in my laboratory research and its evolution as well as contributing significantly to the development of the LIPID MAPS initiative. These included experience and influences from serving as Editor-in-Chief of the and Chair and President of the Keystone Symposia on Cell and Molecular Biology as well as other experiences in organizing lipid conferences, teaching on lipid structure and mechanism, and earlier formative administrative and leadership experiences. The relevant influences are summarized herein.

摘要

我的实验室在脂质方面的研究集中在磷脂酶和脂质组学上,在许多方面与过去半个世纪脂质领域的发展并行不悖。我在其他地方回顾了我们的研究。在这里,我描述了与重点关注我们实验室研究的主要故事并行的“花絮”或“未采用片段”。我将强调社区活动的重要性,并描述我如何发起并领导脂质代谢物和途径策略(LIPID MAPS)的国际努力。这些辅助活动中的几个对我实验室研究的发现及其演变产生了重大影响,并为 LIPID MAPS 计划的发展做出了重大贡献。其中包括担任《生物化学杂志》主编、细胞与分子生物学基石研讨会主席和总裁,以及组织脂质会议、讲授脂质结构和机制,以及更早的形成性管理和领导经验等方面的经验和影响。相关影响在此概述。

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