Li Gangrong, Wei Qianhui, Wei Shuhua, Zhang Jing, Jin Qingxi, Wang Guozhi, Hu Jiawei, Zhu Yan, Kong Yun, Zhang Qingzhu, Zhao Hongbin, Wei Feng, Tu Hailing
State Key Laboratory of Advanced Materials for Smart Sensing, GRINM Group Co., Ltd., Beijing 100088, China.
GRIMAT Engineering Institute Co., Ltd., Beijing 101407, China.
Nanomaterials (Basel). 2022 Jun 16;12(12):2070. doi: 10.3390/nano12122070.
In this study, we report a pH-responsive hydrogel-modified silicon nanowire field-effect transistor for pH sensing, whose modification is operated by spin coating, and whose performance is characterized by the electrical curve of field-effect transistors. The results show that the hydrogel sensor can measure buffer pH in a repeatable and stable manner in the pH range of 3-13, with a high pH sensitivity of 100 mV/pH. It is considered that the swelling of hydrogel occurring in an aqueous solution varies the dielectric properties of acrylamide hydrogels, causing the abrupt increase in the source-drain current. It is believed that the design of the sensor can provide a promising direction for future biosensing applications utilizing the excellent biocompatibility of hydrogels.
在本研究中，我们报道了一种用于pH传感的pH响应水凝胶修饰的硅纳米线场效应晶体管，其修饰通过旋涂操作，其性能通过场效应晶体管的电曲线来表征。结果表明，该水凝胶传感器在3-13的pH范围内能够以可重复且稳定的方式测量缓冲液pH，具有100 mV/pH的高pH灵敏度。据认为，水凝胶在水溶液中发生的溶胀改变了丙烯酰胺水凝胶的介电特性，导致源漏电流突然增加。据信，该传感器的设计可为未来利用水凝胶优异生物相容性的生物传感应用提供一个有前景的方向。
