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2021年“将老年人纳入临床研究”研讨会的关键建议。

Key recommendations from the 2021 "inclusion of older adults in clinical research" workshop.

作者信息

Petrovsky Darina V, Ðoàn Lan N, Loizos Maria, O'Conor Rachel, Prochaska Micah, Tsang Mazie, Hopman-Droste Rachel, Klinedinst Tara C, Mathur Aarti, Bandeen-Roche Karen, van der Willik Odette, Kritchevsky Stephen B

机构信息

Rutgers University, New Brunswick, NJ, USA.

New York University Grossman School of Medicine, New York, NY, USA.

出版信息

J Clin Transl Sci. 2022 Jan 7;6(1):e55. doi: 10.1017/cts.2022.1. eCollection 2022.

Abstract

Older adults are often underrepresented in clinical research, even though older adults are major consumers of novel therapies. We present major themes and recommendations from the 2021 "Inclusion of Older Adults in Clinical Research" Workshop, convened by the Clinical and Translational Science Award (CTSA) Inclusion of Older Adults as a Model for Special Populations Workgroup and the Research Centers Collaborative Network (RCCN). The goal of this workshop was to develop strategies to assist the research community in increasing the inclusion of older adults in clinical research. Major identified barriers include historical lack of federal guidelines, ageist biases and stereotypes, and lack of recruitment and retention techniques or infrastructure focused on older adults. Three key recommendations emerged: 1) engaging with the policymaking process to further promote inclusion; 2) using the CTSA Workgroup Presentation Materials Library and other resources to overcome ageism, and 3) building institutional capacity to support age inclusion.

摘要

尽管老年人是新型疗法的主要消费者,但在临床研究中,老年人的代表性往往不足。我们展示了由临床与转化科学奖(CTSA)将老年人纳入特殊人群工作组及研究中心协作网络(RCCN)召集的2021年“将老年人纳入临床研究”研讨会的主要主题和建议。本次研讨会的目标是制定策略,以协助研究界增加老年人在临床研究中的纳入比例。已确定的主要障碍包括历史上缺乏联邦指导方针、年龄歧视偏见和刻板印象,以及缺乏针对老年人的招募和保留技术或基础设施。出现了三项关键建议:1)参与决策过程以进一步促进纳入;2)利用CTSA工作组演示材料库和其他资源来克服年龄歧视;3)建立支持年龄纳入的机构能力。

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本文引用的文献

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4
Adequacy of Inclusion of Older Adults in NIH-Funded Phase III Clinical Trials.
J Am Geriatr Soc. 2019 Feb;67(2):218-222. doi: 10.1111/jgs.15786. Epub 2019 Jan 29.
5
The 5Ts: Preliminary Development of a Framework to Support Inclusion of Older Adults in Research.
J Am Geriatr Soc. 2019 Feb;67(2):342-346. doi: 10.1111/jgs.15785. Epub 2019 Jan 29.
6
Inclusion Across the Lifespan: NIH Policy for Clinical Research.
JAMA. 2018 Oct 16;320(15):1535-1536. doi: 10.1001/jama.2018.12368.
7
Practical Assessment and Management of Vulnerabilities in Older Patients Receiving Chemotherapy: ASCO Guideline for Geriatric Oncology.
J Clin Oncol. 2018 Aug 1;36(22):2326-2347. doi: 10.1200/JCO.2018.78.8687. Epub 2018 May 21.
8
Adaptive designs in clinical trials: why use them, and how to run and report them.
BMC Med. 2018 Feb 28;16(1):29. doi: 10.1186/s12916-018-1017-7.
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New challenges of geriatric cardiology: from clinical to preclinical research.
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