Yuan Yuan, Hou Ziliang, Peng Dan, Xing Zhenchuan, Wang Jinxiang, Zhang Shuai
Department of Pulmonary and Critical Care Medicine, Beijing Luhe Hospital, Capital Medical University, Beijing, China.
Front Med (Lausanne). 2022 Jun 10;9:916817. doi: 10.3389/fmed.2022.916817. eCollection 2022.
Pulmonary actinomycosis (PA), a chronic indolent infection, is a diagnostic challenge. is a relatively rare Actinomyces species isolated from various clinical samples.
A 47-year-old patient presented with a 3-month history of mucopurulent expectoration and dyspnea and a 3-day history of fever up to 39.0°C. He had dental caries and a history of alcoholism. Computed tomography (CT) images of the chest revealed a consolidation shadow in the right upper and middle lobes, with necrosis containing foci of air. was isolated from bronchoalveolar lavage fluid (BALF) culture and was identified by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. He received treatment with intravenous piperacillin-sulbactam for 10 days and oral amoxicillin-clavulanate for 7 months. His clinical condition had considerably improved. The consolidation shadow was gradually absorbed.
Early diagnosis and treatment of pulmonary actinomycosis are crucial. Bronchoscopy plays a key role in the diagnostic process, and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF/MS) is an accurate tool for identification.
肺放线菌病（PA）是一种慢性隐匿性感染，诊断具有挑战性。[此处原文缺失相关放线菌物种的具体信息]是从各种临床样本中分离出的相对罕见的放线菌物种。
一名47岁患者有3个月的黏液脓性咳痰和呼吸困难病史，以及3天高达39.0°C的发热病史。他有龋齿和酗酒史。胸部计算机断层扫描（CT）图像显示右上叶和中叶有实变影，伴有含气灶的坏死。[此处原文缺失相关放线菌物种的具体信息]从支气管肺泡灌洗（BALF）培养物中分离出来，并通过基质辅助激光解吸/电离飞行时间质谱法进行鉴定。他接受了静脉注射哌拉西林 - 舒巴坦治疗10天和口服阿莫西林 - 克拉维酸治疗7个月。他的临床状况有了显著改善。实变影逐渐吸收。
肺放线菌病的早期诊断和治疗至关重要。支气管镜检查在诊断过程中起关键作用，基质辅助激光解吸/电离飞行时间质谱法（MALDI-TOF/MS）是[此处原文缺失相关放线菌物种的具体信息]鉴定的准确工具。
