Bohe M
Res Exp Med (Berl). 1987;187(1):55-8. doi: 10.1007/BF01854969.
The serum levels of immunoreactive pancreatic secretory trypsin inhibitor (irPSTI) and immunoreactive cationic trypsin (irCT) were measured in 14 patients admitted for severe acute attacks of ulcerative colitis. Patients with acute colitis had significantly higher irPSTI levels in serum (35 micrograms/l) as compared with controls (11.5 micrograms/l), while the serum level of irCT was within normal limits. The normal colonic mucosa recently has been shown to contain irPSTI favoring the theory of an extrapancreatic origin of the increased serum levels of irPSTI in patients with severe active ulcerative colitis.
对14例因溃疡性结肠炎严重急性发作入院的患者测定了血清免疫反应性胰分泌性胰蛋白酶抑制剂（irPSTI）和免疫反应性阳离子胰蛋白酶（irCT）水平。与对照组（11.5微克/升）相比，急性结肠炎患者血清中的irPSTI水平显著更高（35微克/升），而irCT的血清水平在正常范围内。最近研究表明，正常结肠黏膜含有irPSTI，这支持了重症活动期溃疡性结肠炎患者血清中irPSTI水平升高源于胰腺外的理论。
