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儿童时期饮料摄入量与年轻人高血压和高脂血症的风险。

Childhood beverage intake and risk of hypertension and hyperlipidaemia in young adults.

机构信息

Department of Nutritional Sciences, University of Connecticut, Storrs, CT, USA.

Department of Statistics, University of Connecticut, Storrs, CT, USA.

出版信息

Int J Food Sci Nutr. 2022 Nov;73(7):954-964. doi: 10.1080/09637486.2022.2091524. Epub 2022 Jun 27.

Abstract

An epidemiological analysis assessing beverage consumption and risk factors for cardiovascular disease was conducted. Participants were 9-16 years old at enrolment, completed food frequency questionnaires in 1996-2001 and self-reported outcomes in 2010-2014. Exclusion criteria included missing data on relevant variables and covariates, prevalent disease before 2005, and implausible/extreme weight or energy intake. Intakes of orange juice, apple/other fruit juice, sugar-sweetened beverages and diet soda were related to the risk of incident hypertension or hyperlipidaemia using Cox proportional hazards regression, adjusting for diet, energy intake, age, smoking, physical activity and body mass index. There were 9,043 participants with 618 cases of hypertension and 850 of hyperlipidaemia in 17 years of mean follow-up. Sugar-sweetened beverage intake but not fruit juice nor diet soda was associated with hypertension (hazard ratio (95% confidence interval): 1.16 (1.03, 1.31)) in males. This study can guide beverage consumption as it relates to early predictors of cardiovascular disease.

摘要

进行了一项评估饮料消费与心血管疾病风险因素的流行病学分析。参与者在入组时年龄为 9-16 岁,在 1996-2001 年完成了食物频率问卷,并在 2010-2014 年报告了结果。排除标准包括相关变量和协变量数据缺失、2005 年前存在现有疾病以及体重或能量摄入不合理/极端。使用 Cox 比例风险回归,根据饮食、能量摄入、年龄、吸烟、体力活动和体重指数,调整橙汁、苹果/其他果汁、含糖饮料和无糖苏打水的摄入量与高血压或高脂血症的发病风险相关。在平均 17 年的随访中,共有 9043 名参与者,其中 618 例患有高血压,850 例患有高脂血症。含糖饮料的摄入与男性的高血压(风险比(95%置信区间):1.16(1.03,1.31))有关,但果汁和无糖苏打水与高血压无关。本研究可以指导饮料消费,因为它与心血管疾病的早期预测因素有关。

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