Tseng Hsiu-Yang, Lizama Jose H, Alvarado Noel A S, Hou Hsin-Han
Department of Mechanical Engineering, National Taiwan University of Science and Technology, Taipei 106, Taiwan.
Graduate Institute of Oral Biology, College of Medicine, National Taiwan University, Taipei 100, Taiwan.
Biomicrofluidics. 2022 Jun 24;16(3):031302. doi: 10.1063/5.0091228. eCollection 2022 May.
The techniques, protocols, and advancements revolving around printed circuit boards (PCBs) have been gaining sustained attention in the realm of micro-total analysis systems (TAS) as more and more efforts are devoted to searching for standardized, highly reliable, and industry-friendly solutions for point-of-care diagnostics. In this Perspective, we set out to identify the current state in which the field of TAS finds itself, the challenges encountered by researchers in the implementation of these technologies, and the potential improvements that can be targeted to meet the current demands. We also line up some trending innovations, such as 3D printing and wearable devices, along with the development of lab-on-PCB to increase the possibility of multifunctional biosensing activities propelled by integrated microfluidic networks for a wider range of applications, anticipating to catalyze the full potential of TAS.
随着越来越多的努力致力于为即时诊断寻找标准化、高度可靠且对行业友好的解决方案，围绕印刷电路板（PCB）的技术、协议和进展在微全分析系统（TAS）领域持续受到关注。在本视角文章中，我们着手确定TAS领域的当前状况、研究人员在实施这些技术时遇到的挑战，以及为满足当前需求可针对的潜在改进。我们还梳理了一些如3D打印和可穿戴设备等的前沿创新，以及基于印刷电路板的实验室（lab-on-PCB）的发展，以增加由集成微流体网络推动的多功能生物传感活动在更广泛应用中的可能性，期望能激发TAS的全部潜力。
