Department of Ophthalmology, Institute of Vision Research, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea Corneal Dystrophy Research Institute, Yonsei University College of Medicine, Seoul, Korea.
Korean J Ophthalmol. 2022 Aug;36(4):338-349. doi: 10.3341/kjo.2022.0025. Epub 2022 Jun 15.
To evaluate the clinical availability of a multifunctional ocular biometric unit, MR-6000, for simultaneous keratometry, tonometry, topography, and pachymetry evaluation, and compare anterior segment measurements with five other devices: autokeratometer (KR-1), Scheimpflug camera (Pentacam HR), swept-source optical coherence tomography (IOLMaster 700), Placido disk scanning-slit topography (Orbscan II), and noncontact tonometry (FT-1000).
Thirty eyes from thirty patients who visited Severance Hospital for cataract surgery were examined using MR6000 and the other devices. The mean keratometry, central corneal thickness (CCT), white-to-white (WTW) distance, and intraocular pressure (IOP) values were compared. Repeated measures analysis of variance, Wilcoxon signed-rank test, intraclass correlation coefficient (ICC), and Bland-Altman plot were used to assess the correlation and agreement between devices.
Thirty eyes of thirty patients were evaluated. Statistically significant differences in mean keratometry between MR6000, KR-1, Pentacam HR, and IOLMaster 700 were not observed (p > 0.05). All five devices, including Orbscan II, had almost perfect agreement in measuring keratometry (ICC > 0.80, p < 0.05). CCT measured by MR-6000 was significantly different from that of Pentacam HR and Orbscan II measurements (p < 0.05) but correlated with that of Pentacam HR and Orbscan II measurements (ICC > 0.60, p < 0.05). The WTW distance measured by MR-6000 was not significantly different from that measured by IOLMaster 700 but was different from that measured by Orbscan II. IOP measured by MR-6000 was not correlated with FT-1000.
Keratometric values obtained through MR-6000 can be used interchangeably with other devices based on good correlation and agreement. However, the CCT, WTW, and IOP values were not interchangeable with a single multifunctional unit for cataract surgery preoperative examination.
评估一款多功能眼生物测量仪 MR-6000 的临床可用性，该仪器可同时进行角膜曲率、眼压、地形图和角膜厚度测量，并将眼前节测量值与其他五种设备进行比较：自动角膜曲率计（KR-1）、Scheimpflug 相机（Pentacam HR）、扫频源光学相干断层扫描仪（IOLMaster 700）、Placido 盘扫描裂隙地形图（Orbscan II）和非接触眼压计（FT-1000）。
对 30 例在首尔峨山医院接受白内障手术的患者的 30 只眼进行了 MR6000 和其他设备的检查。比较平均角膜曲率、中央角膜厚度（CCT）、白对白（WTW）距离和眼压（IOP）值。采用重复测量方差分析、Wilcoxon 符号秩检验、组内相关系数（ICC）和 Bland-Altman 图评估设备之间的相关性和一致性。
评估了 30 例 30 只眼。MR6000 与 KR-1、Pentacam HR 和 IOLMaster 700 之间的平均角膜曲率无统计学差异（p > 0.05）。所有五种设备（包括 Orbscan II）在测量角膜曲率方面具有几乎完美的一致性（ICC > 0.80，p < 0.05）。MR-6000 测量的 CCT 与 Pentacam HR 和 Orbscan II 测量值明显不同（p < 0.05），但与 Pentacam HR 和 Orbscan II 测量值相关（ICC > 0.60，p < 0.05）。MR-6000 测量的 WTW 距离与 IOLMaster 700 测量值无显著差异，但与 Orbscan II 测量值不同。MR-6000 测量的 IOP 与 FT-1000 不相关。
基于良好的相关性和一致性，MR-6000 获得的角膜曲率值可与其他设备互换使用。然而，对于白内障术前检查，单个多功能单元无法互换使用 CCT、WTW 和 IOP 值。
