Tianjin Key Laboratory of Retinal Functions and Diseases, Tianjin Branch of National Clinical Research Center for Ocular Disease, Eye Institute and School of Optometry, Tianjin Medical University Eye Hospital, Tianjin, 300380, China.
Weifang Eye Hospital, National Key Clinical Specialty, Zhengda Guangming Eye Group, Weifang, 261000, China.
Graefes Arch Clin Exp Ophthalmol. 2024 May;262(5):1567-1578. doi: 10.1007/s00417-023-06348-y. Epub 2023 Dec 27.
To assess the differences and similarities in the corneal curvature obtained by two swept-source optical coherence tomography (SS-OCT) devices, Scheimpflug imaging system and one ray tracing aberrometer in patients with cataracts. Moreover, this study aimed to compare the differences in posterior corneal (PK), total corneal (TK) and true net power (TNP) measurements among the IOLMaster 700, CASIA2, and Pentacam.
A total of 200 eyes of 200 patients (116 female, 58%) were enrolled in this study, with a mean age of 65.9 ± 9.5 years. The flattest (Kf), steepest (Ks), and mean cornal powers (Km), J, and J were obtained using two SS-OCT-based biometric devices, one rotating camera system and one ray-tracing aberrometer. The PK, TK and TNP values were also measured using these devices. To evaluate the differences and similarities between the devicves, the Friedman test, Pearson correlation coefficient (r), intraclass coefficient correlation (ICC) and Bland‒Altman plots with 95% limits of agreement (LoA) were used, and boxplots and stacked histograms were generated to describe the distributions of the data.
There were no significant differences between the IOLMaster 700 and Pentacam for any of the keratometry values. Additionally, there were no significant differences between the IOLMaster 700 and iTrace in evaluating J and J. Bland‒Altman plots revealed relatively wide LoA widths, almost larger than 1 diopter for the keratometry values and almost larger than 0.5 diopter for J and J values among the four devices. In terms of PK and TK values, significant differences and low ICCs were found among the three devices.
Although strong correlations and good agreement were found among the IOLMaster700, CASIA2, Pentacam and iTrace for Kf, Ks, Km and J, J, it seems that the measurements should not be used interchangeably because of the wide LoA widths and the presence of significant differences among the devices. Similarly, due to significant differences and low ICCs, the PK, TK and TNP values obtained by IOLMaster 700, CASIA2, and Pentacam should not be used interchangeably.
评估两种扫频源光学相干断层扫描仪（SS-OCT）设备、Scheimpflug 成像系统和一种光线追踪像差仪在白内障患者中获得的角膜曲率的差异和相似之处。此外，本研究旨在比较 IOLMaster 700、CASIA2 和 Pentacam 之间后角膜（PK）、总角膜（TK）和真实净力（TNP）测量值的差异。
本研究共纳入 200 例（116 例女性，58%）200 只眼的患者，平均年龄为 65.9±9.5 岁。使用两种基于 SS-OCT 的生物测量仪、一种旋转相机系统和一种光线追踪像差仪获得最平坦（Kf）、最陡峭（Ks）和平均角膜力量（Km）、J 和 J 值。还使用这些设备测量 PK、TK 和 TNP 值。为了评估设备之间的差异和相似性，使用 Friedman 检验、Pearson 相关系数（r）、组内系数相关（ICC）和 Bland-Altman 图（95%一致性界限（LoA）），并生成箱线图和堆叠直方图来描述数据分布。
IOLMaster 700 和 Pentacam 在任何角膜曲率值方面均无显著差异。此外，IOLMaster 700 和 iTrace 在评估 J 和 J 方面也无显著差异。Bland-Altman 图显示，在这四种设备中，角膜曲率值的 LoA 宽度相对较宽，几乎大于 1 屈光度，而 J 和 J 值的 LoA 宽度几乎大于 0.5 屈光度。在 PK 和 TK 值方面，三种设备之间存在显著差异和低 ICC。
尽管 IOLMaster700、CASIA2、Pentacam 和 iTrace 之间在 Kf、Ks、Km 和 J、J 方面存在较强的相关性和良好的一致性，但由于 LoA 宽度较宽且设备之间存在显著差异，因此似乎不应将这些测量值互换使用。同样，由于存在显著差异和低 ICC，因此不应将 IOLMaster 700、CASIA2 和 Pentacam 获得的 PK、TK 和 TNP 值互换使用。
