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基于深度神经网络和迁移学习的乳腺癌计算机辅助诊断。

Computer-aided diagnosis for breast cancer classification using deep neural networks and transfer learning.

机构信息

Computer Sciences Department, College of Computer and Information Sciences, Princess Nourah bint Abdulrahman University (PNU), PO Box 84428, Riyadh 11671, Saudi Arabia.

Department of Information Systems, College of Computer and Information Sciences, Princess Nourah bint Abdulrahman University (PNU), PO Box 84428, Riyadh 11671, Saudi Arabia.

出版信息

Comput Methods Programs Biomed. 2022 Aug;223:106951. doi: 10.1016/j.cmpb.2022.106951. Epub 2022 Jun 16.

Abstract

BACKGROUND AND OBJECTIVE

Many developed and non-developed countries worldwide suffer from cancer-related fatal diseases. In particular, the rate of breast cancer in females increases daily, partially due to unawareness and undiagnosed at the early stages. A proper first breast cancer treatment can only be provided by adequately detecting and classifying cancer during the very early stages of its development. The use of medical image analysis techniques and computer-aided diagnosis may help the acceleration and the automation of both cancer detection and classification by also training and aiding less experienced physicians. For large datasets of medical images, convolutional neural networks play a significant role in detecting and classifying cancer effectively.

METHODS

This article presents a novel computer-aided diagnosis method for breast cancer classification (both binary and multi-class), using a combination of deep neural networks (ResNet 18, ShuffleNet, and Inception-V3Net) and transfer learning on the BreakHis publicly available dataset.

RESULTS AND CONCLUSIONS

Our proposed method provides the best average accuracy for binary classification of benign or malignant cancer cases of 99.7%, 97.66%, and 96.94% for ResNet, InceptionV3Net, and ShuffleNet, respectively. Average accuracies for multi-class classification were 97.81%, 96.07%, and 95.79% for ResNet, Inception-V3Net, and ShuffleNet, respectively.

摘要

背景与目的

全球许多发达国家和发展中国家都面临着与癌症相关的致命疾病。特别是,女性乳腺癌的发病率每天都在增加,部分原因是早期缺乏意识和未被诊断。只有在癌症发展的早期阶段进行充分的检测和分类,才能提供适当的首次乳腺癌治疗。医学图像分析技术和计算机辅助诊断的使用可以通过培训和辅助经验较少的医生,帮助加速和实现癌症的检测和分类的自动化。对于大型医学图像数据集,卷积神经网络在有效检测和分类癌症方面发挥着重要作用。

方法

本文提出了一种新的基于深度神经网络(ResNet 18、ShuffleNet 和 Inception-V3Net)和在公开的 BreakHis 数据集上进行迁移学习的计算机辅助乳腺癌分类(二分类和多分类)诊断方法。

结果与结论

我们提出的方法在良性或恶性癌症病例的二分类中提供了最佳的平均准确率,ResNet、InceptionV3Net 和 ShuffleNet 的准确率分别为 99.7%、97.66%和 96.94%。ResNet、Inception-V3Net 和 ShuffleNet 的多分类平均准确率分别为 97.81%、96.07%和 95.79%。

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