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压力知觉与增强的认知功能和降低精神病理学风险有关吗?检验应激假说。

Is perceived stress linked to enhanced cognitive functioning and reduced risk for psychopathology? Testing the hormesis hypothesis.

机构信息

Department of Human Development and Family Science, University of Georgia, Dawson Hall, 305 Sanford Drive, Athens, GA 30602, United States; Youth Development Institute, University of Georgia, Room 208, 105 Foster Road (Pound Hall), Athens, GA 30606, United States; Behavioral and Cognitive Neuroscience Program, University of Georgia, Athens, GA, United States.

Department of Human Development and Family Science, University of Georgia, Dawson Hall, 305 Sanford Drive, Athens, GA 30602, United States; Youth Development Institute, University of Georgia, Room 208, 105 Foster Road (Pound Hall), Athens, GA 30606, United States.

出版信息

Psychiatry Res. 2022 Aug;314:114644. doi: 10.1016/j.psychres.2022.114644. Epub 2022 May 20.

Abstract

Extensive research documents the impact of psychosocial stress on risk for the development of psychiatric symptoms across one's lifespan. Further, evidence exists that cognitive functioning mediates this link. However, a growing body of research suggests that limited stress can result in cognitive benefits that may contribute to resilience. The hypothesis that low-to-moderate levels of stress are linked to more adaptive outcomes has been referred to as hormesis. Using a sample of young adults from the Human Connectome Project (N = 1,206, 54.4% female, M = 28.84), the present study aims to test the hormetic effect between low-to-moderate perceived stress and psychopathological symptoms (internalizing and externalizing symptoms), as well as to cross-sectionally explore the intermediate role of cognitive functioning in this effect. Results showed cognitive functioning as a potential intermediating mechanism underlying the curvilinear associations between perceived stress and externalizing, but not internalizing, behaviors. This study provides preliminary support for the benefits of limited stress to the process of human resilience.

摘要

大量研究文献证明,在人的一生中心理社会压力会对精神症状的发展产生影响。此外,有证据表明认知功能在这一联系中起中介作用。然而,越来越多的研究表明,有限的压力可以带来认知上的好处,从而有助于恢复力。低至中等水平的压力与更适应的结果有关的假设被称为应激。本研究使用来自人类连接组计划的年轻成年人样本(N=1206,女性占 54.4%,M=28.84),旨在测试低至中等程度的感知压力与心理病理症状(内化和外化症状)之间的应激效应,以及在这种效应中交叉探讨认知功能的中间作用。结果表明,认知功能是感知压力与外化行为之间的曲线关联的潜在中介机制,但与内化行为无关。这项研究初步支持了有限压力对人类适应力过程的益处。

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