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COVID-19 替代药物的临床试验。

Clinical Trials on Alternative Medicines for COVID-19.

机构信息

College of Science and Engineering, Hamad Bin Khalifa University, Doha, Qatar.

Department of Petroleum Engineering, Texas A&M University, Doha, Qatar.

出版信息

Stud Health Technol Inform. 2022 Jun 29;295:366-369. doi: 10.3233/SHTI220740.

DOI:10.3233/SHTI220740
PMID:35773886
Abstract

In this study, we addressed the alternative medications that have been targeted in the clinical trials (CTs) to be evidenced as an adjuvant treatment against COVID-19. Based on the outcomes from CTs, we found that dietary supplements such as Lactoferrin, and Probiotics (as SivoMixx) can play a role enhancing the immunity thus can be used as prophylactics against COVID-19 infection. Vitamin D was proven as an effective adjuvant treatment against COVID-19, while Vitamin C role is uncertain and needs more investigation. Herbals such as Guduchi Ghan Vati can be used as prophylactic, while Resveratrol can be used to reduce the hospitalization risk of COVID-19 patients. On the contrary, there were no clinical improvements demonstrated when using Cannabidiol. This study is a part of a two-phase research study. In the first phase, we gathered evidence-based information on alternative therapeutics for COVID-19 that are under CT. In the second phase, we plan to build a mobile health application that will provide evidence based alternative therapy information to health consumers.

摘要

在这项研究中,我们针对临床试验(CT)中针对的替代药物进行了研究,以证明其作为 COVID-19 辅助治疗的功效。根据 CT 的结果,我们发现膳食补充剂,如乳铁蛋白和益生菌(如 SivoMixx)可以增强免疫力,因此可以用作 COVID-19 感染的预防措施。维生素 D 已被证明是 COVID-19 的有效辅助治疗方法,而维生素 C 的作用尚不确定,需要进一步研究。草药如 Guduchi Ghan Vati 可用于预防,而白藜芦醇可用于降低 COVID-19 患者的住院风险。相反,使用大麻二酚并未显示出临床改善。本研究是一项两阶段研究的一部分。在第一阶段,我们收集了 CT 中针对 COVID-19 的替代疗法的循证信息。在第二阶段,我们计划构建一个移动健康应用程序,为健康消费者提供基于证据的替代治疗信息。

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Clinical Trials on Alternative Medicines for COVID-19.COVID-19 替代药物的临床试验。
Stud Health Technol Inform. 2022 Jun 29;295:366-369. doi: 10.3233/SHTI220740.
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Clinical Evidence on the Potential Beneficial Effects of Diet and Dietary Supplements against COVID-19 Infection Risk and Symptoms' Severity.
临床证据表明,饮食和膳食补充剂可能对预防 COVID-19 感染风险和减轻症状严重程度有益。
Med Sci (Basel). 2024 Feb 17;12(1):11. doi: 10.3390/medsci12010011.
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COVID-19Base v3: Update of the knowledgebase for drugs and biomedical entities linked to COVID-19.COVID-19Base v3:与 COVID-19 相关药物和生物医学实体知识库的更新。
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