[一次超大剂量服用后因普罗替林和氟哌啶醇导致的致命中毒]
[Fatal poisoning by protriptyline and haloperidol following an extreme overdose].
作者信息
Fechner G, Magureanu I, Aderjan R, Schmidt G
出版信息
Z Rechtsmed. 1986;97(4):277-83. doi: 10.1007/BF00200607.
PMID:3577435
Abstract
In this paper the authors report on a case of lethal suicidal toxification with protriptyline and haloperidol after oral ingestion. Gas chromatographic and radioimmunologic investigations were used for quantitative determination of protriptyline and haloperidol in blood, urine, and tissues. The highest concentrations were found in lung and liver. These concentrations are discussed with reference to the cause of death.
摘要
本文中作者报告了一例口服普罗替林和氟哌啶醇致死性自杀中毒的病例。采用气相色谱法和放射免疫法对血液、尿液和组织中的普罗替林和氟哌啶醇进行定量测定。在肺和肝脏中发现了最高浓度。结合死亡原因对这些浓度进行了讨论。
相似文献
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[Fatal poisoning by protriptyline and haloperidol following an extreme overdose].[一次超大剂量服用后因普罗替林和氟哌啶醇导致的致命中毒]
Z Rechtsmed. 1986;97(4):277-83. doi: 10.1007/BF00200607.
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Isolation of 10, 11-epoxide of protriptyline in rat urine after protriptyline administration.在给予普罗替林后，从大鼠尿液中分离出普罗替林的10, 11 - 环氧化物。
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Blood and tissue concentrations of tricyclic antidepressant drugs in post mortem cases: literature survey and a study of forty deaths.三环类抗抑郁药物在尸检案例中的血液及组织浓度：文献综述与40例死亡病例研究
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Haloperidol: fifteen years of clinical experience.氟哌啶醇：十五年临床经验
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Toxicology of some autopsy cases involving tricyclic antidepressant drugs.
Z Rechtsmed. 1974;74(4):261-6. doi: 10.1007/BF02114837.
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Relationship between age and tricyclic antidepressant plasma levels.年龄与三环类抗抑郁药血浆水平之间的关系。
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10
Pharmacokinetic aspects of protriptyline plasma levels.普罗替林血药浓度的药代动力学方面
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