Chakrabartty Ishani, Mohanta Yugal Kishore, Nongbet Amilia, Mohanta Tapan Kumar, Mahanta Saurov, Das Nibedita, Saravanan Muthupandian, Sharma Nanaocha
Department of Applied Biology, School of Biological Sciences, University of Science and Technology Meghalaya (USTM), Meghalaya, India.
Department of Botany, School of Biological Sciences, University of Science and Technology Meghalaya (USTM), Meghalaya, India.
Front Pharmacol. 2022 Jun 14;13:894814. doi: 10.3389/fphar.2022.894814. eCollection 2022.
In the current scenario, cardiovascular disease (CVD) is one of the most life-threatening diseases that has caused high mortality worldwide. Several scientists, researchers, and doctors are now resorting to medicinal plants and their metabolites for the treatment of different diseases, including CVD. The present review focuses on one such family of medicinal plants, called Lamiaceae, which has relieving and preventive action on CVD. Lamiaceae has a cosmopolitan distribution and has great importance in the traditional system of medicine. Lamiaceae members exhibit a wide range of activities like antioxidant, antihyperlipidemic, vasorelaxant, and thrombolytic effect, both and -these are mechanisms that contribute to different aspects of CVD including stroke, heart attack, and others. These plants harbour an array of bioactive compounds like phenolic acids, flavonoids, alkaloids, and other phytochemicals responsible for these actions. The review also highlights that these plants are a rich source of essential nutrients and minerals like omega-3 and hence, can serve as essential sources of functional foods-this can have an additional role in the prevention of CVDs. However, limitations still exist, and extensive research needs to be conducted on the Lamiaceae family in the quest to develop new and effective plant-based drugs and functional foods that can be used to treat and prevent cardiovascular diseases worldwide.
在当前情况下，心血管疾病（CVD）是全球范围内导致高死亡率的最具生命威胁的疾病之一。现在，一些科学家、研究人员和医生正求助于药用植物及其代谢产物来治疗包括心血管疾病在内的各种疾病。本综述聚焦于一类名为唇形科的药用植物，其对心血管疾病具有缓解和预防作用。唇形科植物分布广泛，在传统医学体系中具有重要意义。唇形科植物成员表现出广泛的活性，如抗氧化、抗高血脂、血管舒张和溶栓作用，这些作用机制有助于心血管疾病不同方面的防治，包括中风、心脏病发作等。这些植物含有一系列生物活性化合物，如酚酸、黄酮类、生物碱和其他负责这些作用的植物化学物质。该综述还强调，这些植物富含ω-3等必需营养素和矿物质，因此可作为功能性食品的重要来源——这在预防心血管疾病方面可发挥额外作用。然而，仍然存在局限性，为了开发可用于全球治疗和预防心血管疾病的新型有效植物性药物和功能性食品，仍需对唇形科植物进行广泛研究。
