Martinelli P, Gabellini A S, Gulli M R, Lugaresi E
Acta Neurol Scand. 1987 Feb;75(2):106-11. doi: 10.1111/j.1600-0404.1987.tb07903.x.
Two hundred consecutive patients affected by essential tremor (ET), referred to the Movement Disorders Center of the University of Bologna between January 1977 and December 1981, were studied to identify the different clinical features of this disorder, and its associated neurological signs. In this series, 169 patients suffered from typical essential tremor (TET); in the other 31 cases uncommon clinical features were detected: 25 presented postural, action and rest tremor (continuous tremor: CT); 5 had orthostatic tremor (OT) and 1 was affected by writing tremor (WT). Buccolinguofacial dyskinesias (BLFD) were associated with ET in 19 cases; 2 presented dystonia, and in 6 mild extrapyramidal signs were detected. Uncommon types of tremor: ET plus BLFD and ET associated with extrapyramidal signs had an higher incidence in older people. No patient developed Parkinson's disease (PD) during the follow-up period (2-5 years).
对1977年1月至1981年12月间转诊至博洛尼亚大学运动障碍中心的200例特发性震颤（ET）患者进行了研究，以确定该疾病的不同临床特征及其相关的神经系统体征。在这组病例中，169例患有典型特发性震颤（TET）；在其他31例中，检测到不常见的临床特征：25例出现姿势性、动作性和静止性震颤（持续性震颤：CT）；5例有直立性震颤（OT），1例受书写震颤（WT）影响。19例颊舌面部运动障碍（BLFD）与ET相关；2例出现肌张力障碍，6例检测到轻度锥体外系体征。不常见的震颤类型：ET加BLFD和与锥体外系体征相关的ET在老年人中发病率较高。随访期间（2 - 5年）无患者发生帕金森病（PD）。
