Barcelona Institute for Global Health (ISGlobal), Hospital Clínic, University of Barcelona, Barcelona, Spain.
Graduate School of Public Health & Health Policy, City University of New York (CUNY), New York, NY, US.
Nat Commun. 2022 Jul 1;13(1):3801. doi: 10.1038/s41467-022-31441-x.
The COVID-19 pandemic continues to impact daily life, including health system operations, despite the availability of vaccines that are effective in greatly reducing the risks of death and severe disease. Misperceptions of COVID-19 vaccine safety, efficacy, risks, and mistrust in institutions responsible for vaccination campaigns have been reported as factors contributing to vaccine hesitancy. This study investigated COVID-19 vaccine hesitancy globally in June 2021. Nationally representative samples of 1,000 individuals from 23 countries were surveyed. Data were analyzed descriptively, and weighted multivariable logistic regressions were used to explore associations with vaccine hesitancy. Here, we show that more than three-fourths (75.2%) of the 23,000 respondents report vaccine acceptance, up from 71.5% one year earlier. Across all countries, vaccine hesitancy is associated with a lack of trust in COVID-19 vaccine safety and science, and skepticism about its efficacy. Vaccine hesitant respondents are also highly resistant to required proof of vaccination; 31.7%, 20%, 15%, and 14.8% approve requiring it for access to international travel, indoor activities, employment, and public schools, respectively. For ongoing COVID-19 vaccination campaigns to succeed in improving coverage going forward, substantial challenges remain to be overcome. These include increasing vaccination among those reporting lower vaccine confidence in addition to expanding vaccine access in low- and middle-income countries.
尽管疫苗的有效性大大降低了死亡和重症疾病的风险，但 COVID-19 大流行仍在继续影响日常生活，包括卫生系统的运作。人们对 COVID-19 疫苗的安全性、有效性、风险以及对负责疫苗接种活动的机构的信任度存在误解，这些因素被认为是导致疫苗犹豫的原因。本研究于 2021 年 6 月调查了全球范围内对 COVID-19 疫苗的犹豫态度。对 23 个国家的 1000 名具有代表性的个体进行了全国性抽样调查。对数据进行了描述性分析，并使用加权多变量逻辑回归来探讨与疫苗犹豫的关联。结果显示，在 23000 名受访者中，超过四分之三（75.2%）表示接受疫苗，高于一年前的 71.5%。在所有国家中，疫苗犹豫与对 COVID-19 疫苗安全性和科学的缺乏信任以及对其有效性的怀疑有关。对疫苗持犹豫态度的受访者也强烈反对接种疫苗的要求；分别有 31.7%、20%、15%和 14.8%的人赞成在国际旅行、室内活动、就业和公立学校中，要求接种疫苗才能获得这些活动的参与资格。为了使正在进行的 COVID-19 疫苗接种运动在提高覆盖率方面取得成功，仍需克服许多挑战。除了扩大低收入和中等收入国家的疫苗接种范围外，还需要提高对疫苗信心较低的人群的接种率。
