School of Medicine, Huzhou University, Zhejiang, China.
Department of Nursing, Gregory Catholic Hospital, Buduburam, Central Region, Ghana.
Animal Model Exp Med. 2022 Dec;5(6):502-512. doi: 10.1002/ame2.12256. Epub 2022 Jul 6.
Generalized anxiety disorder (GAD) has harmful effects on physical and mental health and quality of life. Coloring therapy has been reported to have a positive effect on improving patient anxiety and depression. But there are no reported clinical trials examining their effectiveness as a treatment for GAD. This study was planned to evaluate the effectiveness of coloring therapy combined with conventional therapy in improving anxiety, depression, and positive and negative emotions with GAD. This randomized controlled study comprising 88 GAD patients was selected for intervention in different wards. The control group (n = 45) was given conventional antianxiety medication and physical therapy, and the experimental group (n = 43) received coloring therapy combined with conventional therapy. The Self-Rating Depression Scale, Self-Rating Anxiety Scale (SAS), Hamilton Depression Scale, Hamilton Anxiety Scale (HAMA), and Positive and Negative Affect Scale were assessed in both groups before and 3 weeks after the intervention. After the intervention, there were statistical differences in intra- and inter-group comparisons of anxiety, depression, and positive and negative mood scales in the experimental and control groups (p < .05). The minus in anxiety/positive emotions pre- and postintervention in the experimental group was statistically significant compared to that in anxiety/positive emotions pre- and postintervention in the control group (HAMA: d = 1.45, 95% confidence interval [CI] (0.34, 2.57), p = .011; SAS: d = 3.87, 95% CI (1.73,6.00), p = .001; positive: d = 1.76, 95% CI (0.17, 3.34), p = .030). The minus in depressive/negative emotions pre- and postintervention in the experimental group was not statistically significant compared with that in depressive/negative emotions pre- and postintervention in the control group (p > .05). For GAD patients, adding coloring therapy based on conventional drug therapy and physical therapy can not only reduce depression and negative emotions but also have better effects on reducing anxiety and improving positive emotions than conventional therapy.
广泛性焦虑障碍(GAD)对身心健康和生活质量有不良影响。有报道称,涂色疗法对改善患者焦虑和抑郁有积极作用。但目前尚无临床研究报道其作为 GAD 治疗方法的有效性。本研究旨在评估涂色疗法联合常规疗法改善 GAD 患者焦虑、抑郁及正性负性情绪的疗效。
这是一项随机对照研究,共纳入 88 例 GAD 患者,分别在不同病房进行干预。对照组(n=45)给予常规抗焦虑药物和物理治疗,实验组(n=43)给予涂色疗法联合常规治疗。在干预前和干预后 3 周,两组均采用抑郁自评量表(SDS)、焦虑自评量表(SAS)、汉密尔顿抑郁量表(HAMD)、汉密尔顿焦虑量表(HAMA)和正性负性情绪量表(PANAS)进行评估。
干预后,实验组和对照组焦虑、抑郁及正性负性情绪量表的组内和组间比较均有统计学差异(p<.05)。实验组干预前后焦虑/正性情绪评分的差值与对照组比较有统计学意义(HAMA:d=1.45,95%置信区间[CI](0.34,2.57),p=0.011;SAS:d=3.87,95% CI(1.73,6.00),p=0.001;正性:d=1.76,95% CI(0.17,3.34),p=0.030)。实验组干预前后抑郁/负性情绪评分的差值与对照组比较无统计学意义(p>.05)。
对于 GAD 患者,在常规药物治疗和物理治疗的基础上增加涂色疗法,不仅能降低抑郁和负性情绪,而且在降低焦虑、改善正性情绪方面的效果优于常规治疗。