Trent Cardiac Centre, Nottingham City Hospital, Nottingham University Hospitals NHS Trust, United Kingdom.
Trent Cardiac Centre, Nottingham City Hospital, Nottingham University Hospitals NHS Trust, United Kingdom.
Hellenic J Cardiol. 2022 Sep-Oct;67:36-41. doi: 10.1016/j.hjc.2022.07.001. Epub 2022 Jul 4.
COVID-19 had a devastating impact on patients with severe aortic stenosis (AS). Like many cardiac procedures, transcatheter aortic valve replacement (TAVR) services were suspended during the first wave of COVID-19. We took the opportunity to evaluate the clinical outcomes and identify any delays at different stages of the TAVR pathway during the COVID-19 pandemic.
Prospectively collected data on 210 consecutive TAVR patients between March 2019 and March 2021 were analysed. We compared the clinical outcomes and 30-day mortality rates of TAVR cases pre-pandemic and during the pandemic. We also looked to identify any time lags from the initial referral to respective stages of the TAVR workup.
A total of 134 patients underwent TAVR prior to the national lockdown (March 2019-March 2020), compared to 76 patients during COVID-19 (April 2020-April 2021). Success rates of TAVR were similar (99% prior to the pandemic and 97.4% during COVID-19). The 30-day survival rates were 98.6% and 94.7%, respectively. Median length of stay post TAVR was 2 days during COVID-19 and 2.5 days prior to the pandemic (p = 0.064). Patients were seen quicker in clinic (median of 33 days) during COVID-19, compared to 51 days before COVID-19 (p = 0.044). No significant difference in times from referral to discussion at TAVR multidisciplinary team (MDT) meetings, CT Aortogram and TAVR implantation, in both groups.
Reconfiguring the patient pathway during COVID-19 allowed TAVR to be performed safely, with a similar success rate and no excess complications or increased 30-day mortality. There proved to be no delay in the respective stages of patient TAVR workup, during the pandemic.
COVID-19 对严重主动脉瓣狭窄(AS)患者造成了毁灭性的影响。与许多心脏手术一样,经导管主动脉瓣置换术(TAVR)服务在 COVID-19 的第一波疫情期间暂停。我们借此机会评估了临床结果,并确定了在 COVID-19 大流行期间 TAVR 途径的不同阶段是否存在任何延误。
前瞻性收集了 2019 年 3 月至 2021 年 3 月期间 210 例连续 TAVR 患者的数据。我们比较了大流行前和大流行期间 TAVR 病例的临床结果和 30 天死亡率。我们还试图确定从最初转诊到 TAVR 检查的各个阶段的任何时间延迟。
共有 134 例患者在全国封锁前(2019 年 3 月至 2020 年 3 月)接受了 TAVR,而在 COVID-19 期间(2020 年 4 月至 2021 年 4 月)有 76 例患者接受了 TAVR。TAVR 的成功率相似(大流行前为 99%,COVID-19 期间为 97.4%)。30 天生存率分别为 98.6%和 94.7%。COVID-19 期间 TAVR 后中位住院时间为 2 天,大流行前为 2.5 天(p=0.064)。COVID-19 期间患者在诊所就诊更快(中位数为 33 天),而 COVID-19 前为 51 天(p=0.044)。两组患者从转诊到 TAVR 多学科团队(MDT)会议、CT 主动脉造影和 TAVR 植入的讨论时间均无明显差异。
在 COVID-19 期间重新配置患者途径可安全地进行 TAVR,成功率相似,无额外并发症或增加 30 天死亡率。在大流行期间,TAVR 患者检查的各个阶段都没有被延迟。