Sethi Ankur, Elmariah Sammy, Gunnarsson Candace, Ryan Michael, Chikermane Soumya, Thompson Christin, Russo Mark
Division of Cardiology, Department of Medicine, Robert Wood Johnson University Hospital, New Brunswick, New Jersey.
Division of Cardiology, Department of Medicine, University of California San Francisco (S.E.).
Struct Heart. 2024 Jun 12;8(6):100321. doi: 10.1016/j.shj.2024.100321. eCollection 2024 Nov.
Aortic stenosis (AS) is a prevalent valvular disorder necessitating timely intervention, particularly when symptomatic. Aortic valve replacement (AVR) is the recommended treatment, but delays in access to AVR are common and linked to adverse outcomes and increased health care costs. This study aims to assess the health care cost burden associated with delaying transcatheter AVR (TAVR) in Medicare Advantage beneficiaries with clinically significant AS.
This retrospective database study utilized the Optum de-identified U.S. claims database, encompassing Medicare Advantage enrollees. Patients aged 65 years or older were identified as having AS based on medical billing codes and were required to have a record of syncope, dyspnea, fatigue, chest pain/angina, or heart failure prior to, on or within 30 days of their incident AS diagnosis. Total health care costs were analyzed over a 2-year period, regressed against the delay in receiving TAVR, and adjusted for covariates. In the 4105 patients meeting study inclusion criteria, delays in TAVR were associated with a significant increase in health care costs, translating to those waiting 12 months for TAVR incurring an additional cost of $10,080 compared to those receiving TAVR promptly. Non-TAVR related costs largely drove this increase.
Delaying TAVR in clinically significant AS patients is associated with higher health care costs, emphasizing the need for timely interventions. Addressing delays in TAVR access and optimizing pre-TAVR workup can potentially improve patient outcomes and reduce health care expenditure.
主动脉瓣狭窄(AS)是一种常见的瓣膜疾病,需要及时干预,尤其是出现症状时。主动脉瓣置换术(AVR)是推荐的治疗方法,但获得AVR的延迟很常见,且与不良后果和医疗保健成本增加有关。本研究旨在评估在具有临床显著意义的AS的医疗保险优势受益人中延迟经导管主动脉瓣置换术(TAVR)所带来的医疗保健成本负担。
这项回顾性数据库研究利用了Optum去识别化的美国索赔数据库,该数据库涵盖医疗保险优势参保者。根据医疗计费代码确定65岁及以上的患者患有AS,并要求他们在首次AS诊断之前、之时或之后30天内有晕厥、呼吸困难、疲劳、胸痛/心绞痛或心力衰竭的记录。在2年期间分析总医疗保健成本,针对接受TAVR的延迟进行回归分析,并对协变量进行调整。在符合研究纳入标准的4105名患者中,TAVR的延迟与医疗保健成本的显著增加相关,这意味着等待12个月进行TAVR的患者比立即接受TAVR的患者额外花费10,080美元。非TAVR相关成本在很大程度上推动了这一增长。
在具有临床显著意义的AS患者中延迟TAVR与更高的医疗保健成本相关,这强调了及时干预的必要性。解决TAVR获取方面的延迟并优化TAVR术前检查可能会改善患者预后并降低医疗保健支出。